Evidence map›Paper›PMID 22629128›Full record

ArticleTheScientificWorldJournal2012

Antibiotic synergy interaction against multidrug-resistant Pseudomonas aeruginosa isolated from an abattoir effluent environment.

Etinosa O Igbinosa, Emmanuel E Odjadjare, Isoken H Igbinosa, Phillips O Orhue, May N O Omoigberale, Napoleon I Amhanre

Open access · goldAbstract read
In one paragraph

Article in TheScientificWorldJournal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Hijacking anaerobic metabolism to restore antibiotic efficacy inApplied and environmental microbiology · 2025
    Article
  3. Article
  4. Article
  5. Antimicrobial Resistance in Food Animals and the Environment in Nigeria: A Review.International journal of environmental research and public health · 2018
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Etinosa O IgbinosaDepartment of Microbiology, Ambrose Alli University, Private Mail Bag 14, Ekpoma 310001, Edo State, Nigeria.
Emmanuel E Odjadjare
Isoken H Igbinosa
Phillips O Orhue
May N O Omoigberale
Napoleon I Amhanre
Ambrose Alli University · NGUniversity of Fort Hare · ZAWestern Delta University · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pseudomonas aeruginosa is an opportunistic pathogen in environmental waters with a high prevalence of multidrug resistance. In this study the synergistic efficacy of synergy antibiotic combinations in multidrug-resistant P. aeruginosa strains isolated from an abattoir effluent was investigated. Water samples were processed using membrane filtration; Pseudomonas was isolated with Pseudomonas Isolation Agar and confirmed using polymerase chain reaction with specie-specific primer. Susceptibility studies and in vitro synergy interaction testing were carried out, employing agar dilution and Etest procedure, respectively. Resistance was noted for clinically relevant antipseudomonal agents tested. Finding from antibiotic synergy interaction studies revealed that cefepime, imipenem, and meropenem combined with amikacin resulted in statistically significant (P < 0.0001) in vitro antibiotics synergy interaction, indicating the possible use of this regimen in treatment of pseudomonal infections.

Indexed as

AbattoirsIndustrial WasteWater MicrobiologyAnti-Bacterial AgentsCell SurvivalDrug Resistance, Multiple, BacterialDrug SynergismPseudomonas aeruginosaAnti-Bacterial AgentsIndustrial Waste

Identifiers

PMID22629128
PMCPMC3353294
OpenAlexW2058709466

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.