Evidence map›Paper›PMID 22628541›Full record

SynthesisHeart (British Cardiac Society)2012

An epidemiological appraisal of the association between heart rate variability and particulate air pollution: a meta-analysis.

Nicky Pieters, Michelle Plusquin, Bianca Cox, Michal Kicinski, Jaco Vangronsveld, Tim S Nawrot

Abstract readMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Heart (British Cardiac Society), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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  7. Short-Term Effect of Ambient Temperature and the Risk of Stroke: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2015
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30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nicky PietersHasselt University, Agoralaan Gebouw D, Diepenbeek, Belgium.
Michelle Plusquin
Bianca Cox
Michal Kicinski
Jaco Vangronsveld
Tim S Nawrot

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveStudies on the association between short-term exposure to ambient air pollution and heart rate variability (HRV) suggest that particulate matter (PM) exposure is associated with reductions in measures of HRV, but there is heterogeneity in the nature and magnitude of this association between studies. The authors performed a meta-analysis to determine how consistent this association is. DATA SOURCE: The authors searched the Pubmed citation database and Web of Knowledge to identify studies on HRV and PM. STUDY SELECTION: Of the epidemiologic studies reviewed, 29 provided sufficient details to be considered. The meta-analysis included 18667 subjects recruited from the population in surveys, studies from patient groups, and from occupationally exposed groups. DATA EXTRACTION: Two investigators read all papers and computerised all relevant information.

resultsThe authors computed pooled estimates from a random-effects model. In the combined studies, an increase of 10 μg/m(3) in PM(2.5) was associated with significant reductions in the time-domain measurements, including low frequency (-1.66%, 95% CI -2.58% to -0.74%) and high frequency (-2.44%, 95% CI -3.76% to -1.12%) and in frequency-domain measurements, for SDNN (-0.12%, 95% CI -0.22% to -0.03%) and for rMSSD (-2.18%, 95% CI -3.33% to -1.03%). Funnel plots suggested that no publication bias was present and a sensitivity analysis confirmed the robustness of our combined estimates.

conclusionThe meta-analysis supports an inverse relationship between HRV, a marker for a worse cardiovascular prognosis, and particulate air pollution.

Indexed as

Cardiovascular DiseasesModels, TheoreticalGlobal HealthHeart RateHumansIncidenceParticulate MatterPrognosisParticulate Matter

Identifiers

PMID22628541
PMCPMC3392690

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.