ReviewJournal of mammary gland biology and neoplasia2012
A methodological approach to unravel organ-specific breast cancer metastasis.
Review in Journal of mammary gland biology and neoplasia, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed.
- Coexpression of EphA10 and Gli3 promotes breast cancer cell proliferation, invasion and migration.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2021Article
- Correlation of OGR1 with proliferation and apoptosis of breast cancer cells.Oncology letters · 2019Article
- kshv-mir-k12-1-5p promotes cell growth and metastasis by targeting SOCS6 in Kaposi's sarcoma cells.Cancer management and research · 2019Article
- miR-339-5p inhibits lung adenocarcinoma invasion and migration by directly targeting BCL6.Oncology letters · 2018Article
- Quantitative measurement of breast carcinoma fibrosis for the prediction in the risk of bone metastasis.American journal of translational research · 2018Article
- Expression of and correlation between BCL6 and ZEB family members in patients with breast cancer.Experimental and therapeutic medicine · 2017Article
- Organ-specific isogenic metastatic breast cancer cell lines exhibit distinct Raman spectral signatures and metabolomes.Oncotarget · 2017Article
- EGFR and HER2 signaling in breast cancer brain metastasis.Frontiers in bioscience (Elite edition) · 2016Article
- S6K1 promotes invasiveness of breast cancer cells in a model of metastasis of triple-negative breast cancer.American journal of translational research · 2014Article
- New methods in mammary gland development and cancer: proteomics, epigenetics, symmetric division and metastasis.Breast cancer research : BCR · 2012Article
- Critical questions in mammary gland development, lactational biology and breast cancer.Journal of mammary gland biology and neoplasia · 2012Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Breast cancer is the most commonly diagnosed and the second highest cause of cancer-related mortality. Although major breakthroughs have emerged during the past decades concerning the characterization of major malignant tumors hallmarks, little is known about the molecular process that sustains the most deadly feature of cancer: metastasis to distant organs. In fact, this colonization of tumor cells to secondary sites is not random but rather orientated, and depends on several signalling events that are not fully elucidated yet. Understanding the precise molecular and cellular mechanisms accountable for the specific invasion of tissues by breast cancer cells is likely to be important for developing new therapeutic strategies to effectively prevent metastasis in patients diagnosed with early cancer lesions. Here, we briefly describe a multidisciplinary approach based on the molecular profiling of breast cancer metastases, the elaboration of prognostic gene signatures, the clinical validation and the experimental confirmation using cell and animal models to better address breast cancer metastasis. This methodology can be considered as a useful workflow to identify and validate the genes that trigger and support organ tropism of breast cancer cells during metastasis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.