Evidence map›Paper›PMID 22627859›Full record

ReviewNature reviews. Immunology2012

Emerging concepts in haematopoietic cell transplantation.

Hao Wei Li, Megan Sykes

Abstract readReview
In one paragraph

Review in Nature reviews. Immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. CD8Science advances · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Expansion of human hematopoietic stem cells by inhibiting translation.bioRxiv : the preprint server for biology · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Synthesis of an Anti-CD7 Recombinant Immunotoxin Based on PE24 in CHO andInternational journal of molecular sciences · 2022
    Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Oral manifestations of graft-versus-host disease in patients submitted to allogeneic hematopoietic stem cell transplantation: the experience of a Brazilian Cancer Center.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  19. Vangl2 Promotes Hematopoietic Stem Cell Expansion.Frontiers in cell and developmental biology · 2022
    Article
  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hao Wei LiColumbia Center for Translational Immunology, Columbia University Medical Center, 650 West 168th Street, BB 15-02, New York, New York 10032, USA.
Megan Sykes

Funding

XENOGENIC TOLERANCE IN MICEP01HL018646 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI MADSEN, JOREN C · 1985 to 2019
$37.5M
STATISTICAL COREP01CA111519 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI PREFFER, FREDERIC IRA · 2006 to 2010
$9.3M
Pig to human thymic xenotransplantationR01AI084903 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SYKES, MEGAN · 2010 to 2014
$2.5M
SEPARATION OF GVH AND GVL IN MOUSE MODELSR01CA079989 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI SYKES, MEGAN · 2000 to 2008
$2.2M
NCI NIH HHS P01 CA111519NCI NIH HHS R01 CA079989NHLBI NIH HHS P01 HL018646NIAID NIH HHS R01 AI084903
6 · The paper itself

Abstract

Haematopoietic cell transplantation (HCT) is the most widely used form of cellular therapy. It is the only known cure for some haematological malignancies and has recently been used in additional clinical settings, such as allograft tolerance induction and treatment of autoimmune diseases. Recent advances have enabled HCT in a wider range of patients with improved outcomes. This Review summarizes the latest developments in this therapy, focusing on issues that will affect future advancement.

Indexed as

AnimalsAutoimmune DiseasesFetal BloodGraft vs Host DiseaseHematologic NeoplasmsHematopoietic Stem Cell TransplantationHLA AntigensHumansTransplantation ConditioningHLA Antigens

Identifiers

PMID22627859
PMCPMC4006975

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.