Trial reportJournal of neuroscience methods2012
Effects of 30Hz θ burst transcranial magnetic stimulation on the primary motor cortex.
Trial report in Journal of neuroscience methods, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Efficacy of non-invasive brain stimulation for post-stroke sleep disorders: a systematic review and meta-analysis.Frontiers in neurology · 2024Pooled it
- Current Updates on Newer Forms of Transcranial Magnetic Stimulation in Major Depression.Advances in experimental medicine and biology · 2021Pooled it
- Function-Specific Localization in the Supplementary Motor Area: A Potential Effective Target for Tourette Syndrome.CNS neuroscience & therapeutics · 2025Trial
- Augmentation of fear extinction by theta-burst transcranial magnetic stimulation of the prefrontal cortex in humans.Journal of psychiatry & neuroscience : JPN · 2021Trial
- Theta Burst Stimulation of the Cerebellum Modifies the TMS-Evoked N100 Potential, a Marker of GABA Inhibition.PloS one · 2015Trial
- Height-dependent variation in corticospinal excitability modulation after active but not sham intermittent theta burst stimulation.IBRO neuroscience reports · 2025Article
- Continuous theta burst stimulation at 30 hz does not modulate cortical excitability in a sham-controlled study.Scientific reports · 2024Article
- Continuous theta-burst stimulation over the right dorsolateral prefrontal cortex disrupts fear memory reconsolidation in humans.iScience · 2022Article
- Facilitation of Motor Evoked Potentials in Response to a Modified 30 Hz Intermittent Theta-Burst Stimulation Protocol in Healthy Adults.Brain sciences · 2021Article
- Use of 30-Hz Accelerated iTBS in Drug-Resistant Unipolar and Bipolar Depression in a Public Healthcare Setting: A Case Series.Frontiers in psychiatry · 2021Article
- Intermittent Theta-Burst Stimulation Over the Suprahyoid Muscles Motor Cortex Facilitates Increased Degree Centrality in Healthy Subjects.Frontiers in human neuroscience · 2020Article
- Article
- Intermittent Theta-Burst Stimulation Reverses the After-Effects of Contralateral Virtual Lesion on the Suprahyoid Muscle Cortex: Evidence From Dynamic Functional Connectivity Analysis.Frontiers in neuroscience · 2019Article
- Transcranial Magnetic Stimulation with Intermittent Theta Burst Stimulation Alters Corticospinal Output in Patients with Chronic Incomplete Spinal Cord Injury.Frontiers in neurology · 2017Article
- Theta burst stimulation over premotor cortex in Parkinson's disease: an explorative study on manual dexterity.Journal of neural transmission (Vienna, Austria : 1996) · 2016Article
- Abnormal Cortical Plasticity in Youth with Autism Spectrum Disorder: A Transcranial Magnetic Stimulation Case-Control Pilot Study.Journal of child and adolescent psychopharmacology · 2016Article
- Metaplasticity in human primary somatosensory cortex: effects on physiology and tactile perception.Journal of neurophysiology · 2016Article
- Non-invasive electrical and magnetic stimulation of the brain, spinal cord, roots and peripheral nerves: Basic principles and procedures for routine clinical and research application. An updated report from an I.F.C.N. Committee.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2015Review
- Effect of 30 Hz theta burst transcranial magnetic stimulation on the primary motor cortex in children and adolescents.Frontiers in human neuroscience · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Theta Burst Stimulation (TBS) is a relatively new form of repetitive Transcranial Magnetic Stimulation (TMS) used to probe neuroplasticity in the human cortex. Thirty-Hz TBS, a variation of the originally described 50Hz TBS, has been shown to induce cortical changes in several nonmotor regions. However, its effects over the primary motor cortex have not been examined. Due to TMS device mechanical properties, 30Hz TBS is advantageous over 50Hz TBS in that it can be delivered at higher stimulation intensities. The goal of this pilot study is to examine the neurophysiologic effects of 30Hz TBS on the primary motor cortex (M1) of healthy adults. Eighteen right-handed adults (33±9.0 years; M:F=8:10) completed intermittent TBS (iTBS) or continuous TBS (cTBS) over left M1. TBS was performed with Magstim® SuperRapid2 with stimulation bursts (3 pulses at 30Hz) repeating every 200ms. For iTBS, each 2-s stimulation train was separated by 8s but there was no pause between trains for cTBS. Each TBS consisted of a total of 600 pulses delivered at an intensity of 90%*Resting Motor Threshold. Motor-Evoked Potentials (MEP) in the right first dorsal interosseous muscle were measured before, and one and ten minutes after TBS. Pre/post-TBS MEP amplitudes were compared using repeated-measures ANOVA. MEP amplitudes increased after 30Hz iTBS and decreased after 30Hz cTBS (TBS-Type*Time effect p=0.009). In conclusion, 30Hz TBS induced similar neurophysiologic effects over M1 as conventional 50Hz TBS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.