Evidence map›Paper›PMID 22626501›Full record

ArticleGastroenterology2012

Dead on arrival: understanding the failure of CTLA4-immunoglobulin therapy in inflammatory bowel disease.

Lloyd Mayer, Arthur Kaser, Richard S Blumberg

Abstract readEditorialComment
In one paragraph

Article in Gastroenterology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Pathogenesis of Crohn's disease.F1000prime reports · 2015
    Review
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Lloyd Mayer
Arthur Kaser
Richard S Blumberg

Funding

STRUCTURE-FUNCTION RELATIONSHIPS IN THE ALIMENTARY TRACTP30DK034854 · NIDDK · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WAYNE I LENCER · 1986 to 2026
$32.4M
THE ROLE OF ICSBP IN MUCOSAL IMMUNE RESPONSEP01DK072201 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HARPAZ, NOAM · 2006 to 2015
$14.6M
Regulation of Mucosal LymphocytesR01DK051362 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI Richard S Blumberg, Yu-Hwa Huang Blumberg · 1997 to 2026
$13.5M
INTESTINAL TRANSCYTOSIS OF IGG IN ADULT LIFER01DK053056 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI BLUMBERG, RICHARD S · 1997 to 2021
$10.6M
MOLECULAR CHARACTERIZATION OF MUCOSAL LYMPHOCYTESR01DK044319 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI Richard S Blumberg · 1992 to 2026
$10.4M
Tolerance vs. Allergenicity; Factors Dictating Differing ResponsesU19AI044236 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SAMPSON, HUGH A · 2008 to 2014
$9.8M
Endoplasmic reticulum stress and intestinal inflammationR01DK088199 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI Richard S Blumberg · 2010 to 2026
$9.6M
ORAL TOLERANCE AND COW MILK ALLERGYP01AI044236 · NIAID · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI SAMPSON, HUGH · 1999 to 2007
$7.5M
Characterization of Mucosal LymphocytesR37DK044319 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI BLUMBERG, RICHARD S · 2005 to 2014
$7.2M
Oral Vaccine Platform for Yersinia pestisR01AI084952 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI DATTWYLER, RAYMOND JAMES, MAYER, LLOYD F · 2010 to 2012
$1.2M
Generation and characterization of intestinal CD8+ regulatory T cell linesRC1DK086605 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MAYER, LLOYD F · 2009 to 2010
$988k
Intestinal Immune Regulation by IgG and FcRnR56DK053056 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI BLUMBERG, RICHARD S · 2017 to 2017
$100k
NIAID NIH HHS AI044236NIAID NIH HHS AI084952NIAID NIH HHS P01 AI044236NIAID NIH HHS R01 AI084952NIAID NIH HHS U19 AI044236NIDDK NIH HHS DK044319NIDDK NIH HHS DK051362NIDDK NIH HHS DK053056NIDDK NIH HHS DK072201NIDDK NIH HHS DK086605NIDDK NIH HHS DK088199NIDDK NIH HHS P01 DK072201NIDDK NIH HHS P30 DK034854NIDDK NIH HHS R01 DK044319NIDDK NIH HHS R01 DK051362NIDDK NIH HHS R01 DK053056NIDDK NIH HHS R01 DK088199NIDDK NIH HHS R37 DK044319NIDDK NIH HHS R56 DK053056NIDDK NIH HHS RC1 DK086605
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Colitis, UlcerativeCrohn DiseaseFemaleHumansMale

Identifiers

PMID22626501
PMCPMC3392152

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.