Evidence map›Paper›PMID 22625996›Full record

ArticleAnnals of epidemiology2012

Differential impact of risk factors for women and men on the risk of major depressive disorder.

Bauke T Stegenga, Michael King, Diederick E Grobbee, Francisco Torres-González, Igor Švab, Heidi-Ingrid Maaroos, Miguel Xavier, Sandra Saldivia, Christian Bottomley, Irwin Nazareth and 1 more

Abstract readMulticenter Study
In one paragraph

Article in Annals of epidemiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Bauke T StegengaJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands.
Michael King
Diederick E Grobbee
Francisco Torres-González
Igor Švab
Heidi-Ingrid Maaroos
Miguel Xavier
Sandra Saldivia
Christian Bottomley
Irwin Nazareth
Mirjam I Geerlings

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOur aim is to examine which risk factors have a greater impact in women than in men on the risk of major depressive disorder (MDD) and whether factors differ between a possible recurrent MDD and a first onset of MDD.

methodsProspective cohort study of general practice attendees in seven countries, who were followed up at 6 and 12 months (predictD). Absolute risk differences (interaction contrast) across sex for onset of DSM-IV MDD after 6 or 12 months of follow-up were estimated for 35 risk factors from 7101 participants without MDD at baseline.

resultsA total of 599 participants (80% female) had an onset of MDD at 6 or 12 months. Most risk factors had a greater impact in women than in men on the risk of MDD and were not restricted to a specific class of risk factors. After we stratified for a history of depressive symptoms, we found that the impact of risk factors across sex was generally stronger on possible recurrent MDD than on a first onset of MDD.

conclusionsOur findings may partly account for the observed difference in incidence of MDD between men and women.

Indexed as

Risk FactorsSex FactorsAdolescentAdultAgedFemaleGeneral PracticeHumansIncidenceMajor Depressive DisorderMaleMiddle AgedProspective StudiesYoung Adult

Identifiers

PMID22625996
PMCPMC3657146

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.