Evidence map›Paper›PMID 22625860›Full record

ArticleCurrent biology : CB2012

Pronuclear migration: no attachment? No union, but a futile cycle!

Phuong A Nguyen, Keisuke Ishihara, Martin Wühr, Timothy J Mitchison

Abstract readComment
PubMed Publisher
In one paragraph

Article in Current biology : CB, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Phuong A NguyenDepartment of Systems Biology, Harvard Medical School, Boston, MA 02115, USA. pnguyen@fas.harvard.edu
Keisuke Ishihara
Martin Wühr
Timothy J Mitchison

Funding

MICROTUBULE DYNAMICS AND MITOTIC MECHANISMR01GM039565 · NIGMS · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI MITCHISON, TIMOTHY J · 1988 to 2018
$6.2M
Diversity Supplement: Cytokinesis and RNA segregation in zebrafish developmentR01GM065303 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI PELEGRI, FRANCISCO J · 2002 to 2023
$4.7M
NIGMS NIH HHS R01 GM039565NIGMS NIH HHS R01 GM065303
6 · The paper itself

Abstract

How do pronuclei migrate towards each other? The zebrafish futile cycle gene is shown to encode a maternally expressed membrane protein required for nuclear attachment and migration along the sperm aster.

Indexed as

AnimalsCell NucleusCentrosomeFemaleMaleMembrane ProteinsZebrafishZebrafish ProteinsZygoteLrmp protein, zebrafishMembrane ProteinsZebrafish Proteins

Identifiers

PMID22625860

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.