ReviewCritical reviews in microbiology2012
P450 monooxygenases (P450ome) of the model white rot fungus Phanerochaete chrysosporium.
Review in Critical reviews in microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
50 citing papers in PubMed, 131 citations in OpenAlex.
- Format-Preserving Reduction of Canonical Nonlinear Models.Bulletin of mathematical biology · 2026Article
- Metagenomic profiling of gut microbiome signatures across liver disease stages and HCV-related hepatocellular carcinoma in Egyptian patients.Frontiers in microbiology · 2026Article
- Biodegradation of Emerging Contaminants Controlled by Biological and Chemical Factors.Microorganisms · 2025Review
- Transcriptome response of the white-rot fungus Trametes versicolor to hybrid poplar exhibiting unique lignin chemistry.Fungal biology and biotechnology · 2025Article
- Structure-Function Analysis of the Self-Sufficient CYP102 Family Provides New Insights into Their Biochemistry.International journal of molecular sciences · 2025Article
- Dynamic Monitoring ofPlants (Basel, Switzerland) · 2025Article
- Metabolic mechanism of lignin-derived aromatics in white-rot fungi.Applied microbiology and biotechnology · 2024Review
- Pathway crosstalk between the central metabolic and heme biosynthetic pathways in Phanerochaete chrysosporium.Applied microbiology and biotechnology · 2024Article
- Identification and characterization of methoxy- and dimethoxyhydroquinone 1,2-dioxygenase fromApplied and environmental microbiology · 2024Article
- Recent advances in fungal xenobiotic metabolism: enzymes and applications.World journal of microbiology & biotechnology · 2023Review
- Genomic Comparisons of Two Armillaria Species with Different Ecological Behaviors and Their Associated Soil Microbial Communities.Microbial ecology · 2023Article
- Crystal Structure and Biochemical Analysis of a Cytochrome P450 CYP101D5 fromInternational journal of molecular sciences · 2022Article
- Characterization of two 1,2,4-trihydroxybenzene 1,2-dioxygenases from Phanerochaete chrysosporium.Applied microbiology and biotechnology · 2022Article
- Genome-Wide Analysis of Cytochrome P450s ofJournal of fungi (Basel, Switzerland) · 2022Article
- Robust Profiling of Cytochrome P450s (P450ome) in NotableLife (Basel, Switzerland) · 2022Article
- Environmental and molecular approach to dye industry waste degradation by the ascomycete fungus Nectriella pironii.Scientific reports · 2021Article
- Late-Stage Functionalisation of Polycyclic (Biomolecules · 2021Article
- Biosynthesis and regulation of terpenoids from basidiomycetes: exploration of new research.AMB Express · 2021Review
- Evolution and enrichment of CYP5035 in Polyporales: functionality of an understudied P450 family.Applied microbiology and biotechnology · 2021Article
- Omics analyses and biochemical study of Phlebiopsis gigantea elucidate its degradation strategy of wood extractives.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Phanerochaete chrysosporium, the model white rot fungus, has been the focus of research for the past about four decades for understanding the mechanisms and processes of biodegradation of the natural aromatic polymer lignin and a broad range of environmental toxic chemicals. The ability to degrade this vast array of xenobiotic compounds was originally attributed to its lignin-degrading enzyme system, mainly the extracellular peroxidases. However, subsequent physiological, biochemical, and/or genetic studies by us and others identified the involvement of a peroxidase-independent oxidoreductase system, the cytochrome P450 monooxygenase system. The whole genome sequence revealed an extraordinarily large P450 contingent (P450ome) with an estimated 149 P450s in this organism. This review focuses on the current status of understanding on the P450 monooxygenase system of P. chrysosproium in terms of pre-genomic and post-genomic identification, structural and evolutionary analysis, transcriptional regulation, redox partners, and functional characterization for its biodegradative potential. Future research on this catalytically diverse oxidoreductase enzyme system and its major role as a newly emerged player in xenobiotic metabolism/degradation is discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.