ArticleJournal of the National Cancer Institute. Monographs2012
Multilevel research and the challenges of implementing genomic medicine.
Article in Journal of the National Cancer Institute. Monographs, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Which BRCA genetic testing programs are ready for implementation in health care? A systematic review of economic evaluations.Genetics in medicine : official journal of the American College of Medical Genetics · 2016Pooled it
- Proactive process evaluation of precision medicine platforms: a roadmap.BMJ health & care informatics · 2025Article
- Article
- Acceptability and appropriateness of a risk-tailored organised melanoma screening program: Qualitative interviews with key informants.PloS one · 2023Article
- Advancing the symptom science model with environmental health.Public health nursing (Boston, Mass.) · 2019Article
- Leveraging Implementation Science to Address Health Disparities in Genomic Medicine: Examples from the Field.Ethnicity & disease · 2019Article
- Implementing universal Lynch syndrome screening (IMPULSS): protocol for a multi-site study to identify strategies to implement, adapt, and sustain genomic medicine programs in different organizational contexts.BMC health services research · 2018Article
- Cost Analyses of Genomic Sequencing: Lessons Learned from the MedSeq Project.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2018Article
- From public health genomics to precision public health: a 20-year journey.Genetics in medicine : official journal of the American College of Medical Genetics · 2018Review
- On the readiness of physicians for pharmacogenomics testing: an empirical assessment.The pharmacogenomics journal · 2018Article
- Article
- Physician Experiences and Understanding of Genomic Sequencing in Oncology.Journal of genetic counseling · 2018Article
- Future of Evidence Synthesis in Precision Oncology: Between Systematic Reviews and Biocuration.JCO precision oncology · 2018Article
- The value of genetic testing: beyond clinical utility.Genetics in medicine : official journal of the American College of Medical Genetics · 2017Article
- Participatory epidemiology: the contribution of participatory research to epidemiology.Emerging themes in epidemiology · 2017Review
- Hereditary Cancer: Example of a Public Health Approach to Ensure Population Health Benefits of Genetic Medicine.Healthcare (Basel, Switzerland) · 2016Review
- Identification and utilization of donor and recipient genetic variants to predict survival after HCT: are we ready for primetime?Current hematologic malignancy reports · 2015Review
- Beyond public health genomics: proposals from an international working group.European journal of public health · 2014Article
- What is translational genomics? An expanded research agenda for improving individual and population health.Applied & translational genomics · 2014Article
- Implementation of routine screening for Lynch syndrome in university and safety-net health system settings: successes and challenges.Genetics in medicine : official journal of the American College of Medical Genetics · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Advances in genomics and related fields promise a new era of personalized medicine in the cancer care continuum. Nevertheless, there are fundamental challenges in integrating genomic medicine into cancer practice. We explore how multilevel research can contribute to implementation of genomic medicine. We first review the rapidly developing scientific discoveries in this field and the paucity of current applications that are ready for implementation in clinical and public health programs. We then define a multidisciplinary translational research agenda for successful integration of genomic medicine into policy and practice and consider challenges for successful implementation. We illustrate the agenda using the example of Lynch syndrome testing in newly diagnosed cases of colorectal cancer and cascade testing in relatives. We synthesize existing information in a framework for future multilevel research for integrating genomic medicine into the cancer care continuum.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.