Evidence map›Paper›PMID 22622445›Full record

ArticleJournal of clinical microbiology2012

Evaluation of the New NucliSENS EasyQ KPC test for rapid detection of Klebsiella pneumoniae carbapenemase genes (blaKPC).

Teresa Spanu, Barbara Fiori, Tiziana D'Inzeo, Giulia Canu, Serena Campoli, Tommaso Giani, Ivana Palucci, Mario Tumbarello, Maurizio Sanguinetti, Gian Maria Rossolini

Abstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. From Species to Genes: A New Diagnostic Paradigm.Antibiotics (Basel, Switzerland) · 2024
    Review
  2. Review
  3. Modern Tools for Rapid Diagnostics of Antimicrobial Resistance.Frontiers in cellular and infection microbiology · 2020
    Review
  4. Article
  5. Article
  6. A structural, epidemiological & genetic overview ofThe Indian journal of medical research · 2016
    Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Teresa SpanuInstitutes of Microbiology, Catholic University of the Sacred Heart, Rome, Italy. tspanu@rm.unicatt.it
Barbara Fiori
Tiziana D'Inzeo
Giulia Canu
Serena Campoli
Tommaso Giani
Ivana Palucci
Mario Tumbarello
Maurizio Sanguinetti
Gian Maria Rossolini

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

KPC-type carbapenemases are emerging in Klebsiella pneumoniae and other Gram-negative pathogens worldwide. Rapid and sensitive detection of these resistance determinants has become relevant to clinical management and infection control. We evaluated the bioMérieux EasyQ real-time PCR assay for bla(KPC) detection with 300 members of the Enterobacteriaceae, including 29 control strains producing known carbapenemases and 271 nonreplicate clinical isolates. The EasyQ assay correctly detected all of the 111 isolates harboring bla(KPC) genes, with no false positives, and results were available within 2 h.

Indexed as

beta-Lactam ResistanceBacterial ProteinsBacteriological Techniquesbeta-LactamasesEnterobacteriaceaeEnterobacteriaceae InfectionsHumansMolecular Diagnostic TechniquesReal-Time Polymerase Chain ReactionSensitivity and SpecificityTime FactorsBacterial Proteinsbeta-Lactamasescarbapenemase

Identifiers

PMID22622445
PMCPMC3421519

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.