Evidence map›Paper›PMID 22622368›Full record

ArticleJournal of neural transmission (Vienna, Austria : 1996)2012

Indicators for elevated risk factors for alcohol-withdrawal seizures: an analysis using a random forest algorithm.

Thomas Hillemacher, Helge Frieling, Julia Wilhelm, Annemarie Heberlein, Deniz Karagülle, Stefan Bleich, Bernd Lenz, Johannes Kornhuber

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of neural transmission (Vienna, Austria : 1996), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Thomas HillemacherCenter for Addiction Research-CARe, Department for Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany. hillemacher.thomas@mh-hannover.de
Helge Frieling
Julia Wilhelm
Annemarie Heberlein
Deniz Karagülle
Stefan Bleich
Bernd Lenz
Johannes Kornhuber
Medizinische Hochschule Hannover · DEUniversitätsklinikum Erlangen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcohol-withdrawal seizures (AWS) are an important and relevant complication during detoxification in alcohol-dependent patients. Therefore, it is important to evaluate the individual risk for AWS. We apply a random forest algorithm to assess possible predictive markers in a large sample of 200 alcohol-dependent patients undergoing alcohol withdrawal. This analysis showed that the combination of homocysteine, prolactin, blood alcohol concentration on admission, number of preceding withdrawals, age and the number of cigarettes smoked may successfully predict AWS. In conclusion, the results of this analysis allow for origination of further research, which should include additional biological and psychosocial parameters as well as consumption behaviour.

Indexed as

AlgorithmsAdultAgedAlcohol Withdrawal SeizuresArea Under CurveCentral Nervous System DepressantsEthanolFemaleHomocysteineHumansMaleMiddle AgedPredictive Value of TestsProlactinRisk FactorsYoung AdultCentral Nervous System DepressantsEthanolHomocysteineProlactin

Identifiers

PMID22622368
OpenAlexW2024455556

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.