ArticleJournal of lower genital tract disease2012
Rates of self-reported urinary, gastrointestinal, and pain comorbidities in women with vulvar lichen sclerosus.
Article in Journal of lower genital tract disease, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 37 citations in OpenAlex.
- Lichen sclerosus. Part 1. Guideline of the DGG, DGGG, OEGGG and SGGG (S3-Level, AWMF Registry No. 013-105, July 2025.Geburtshilfe und Frauenheilkunde · 2026Article
- Urinary Incontinence Among Female Patients with Lichen Sclerosus: An Updated Systematic Review and Meta-Analysis.International urogynecology journal · 2026Review
- Is urinary incontinence associated with lichen sclerosus in females? A systematic review and meta-analysis.Skin health and disease · 2021Article
- Comparison of Serum Vitamin D Levels in Relation to Bowel and Bladder Symptoms in Women with Vulvar Diseases.International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 2020Article
- Etiology, Clinical Features, and Diagnosis of Vulvar Lichen Sclerosus: A Scoping Review.Obstetrics and gynecology international · 2020Article
- Anti-Inflammatory and Tissue Regenerative Effects of Topical Treatment with Ozonated Olive Oil/Vitamin E Acetate in Balanitis Xerotica Obliterans.Molecules (Basel, Switzerland) · 2018Observational
- Vulvar lichen sclerosus in women is associated with lower urinary tract symptoms.International urogynecology journal · 2018Article
- Radiation-induced lichen sclerosus of the vulva : First report in the medical literature.Wiener medizinische Wochenschrift (1946) · 2017Article
- Responses to the McGill Pain Questionnaire predict neuropathic pain medication use in women in with vulvar lichen sclerosus.Journal of lower genital tract disease · 2015Article
- The co-occurrence of lichen sclerosus et atrophicus and celiac disease.Indian dermatology online journal · 2014Article
- The impact of vulvar lichen sclerosus on sexual dysfunction.Journal of women's health (2002) · 2014Article
- General health status and incidence of first-onset temporomandibular disorder: the OPPERA prospective cohort study.The journal of pain · 2013Observational
- Agents that act luminally to treat diarrhoea and constipation.Nature reviews. Gastroenterology & hepatology · 2012Review
- Lower Urinary Tract and Functional Bowel Symptoms in Women With Vulvar Diseases and Controls.Female pelvic medicine & reconstructive surgeryArticle
- The Gastrointestinal Pain Pointer: A Valid and Innovative Method to Assess Gastrointestinal Symptoms.Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and AssociatesArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveThe study aimed to determine the prevalences of comorbid disorders in women with vulvar lichen sclerosus. MATERIALS AND
methodsA retrospective review of self-administered questionnaires regarding the health history of 308 women with lichen sclerosus seen at a vulvar clinic between 2006 and 2011 was performed. Responses to questions about urinary (overactive bladder [OAB], urinary incontinence [UI], and stress UI), gastrointestinal (inflammatory bowel diseases, constipation, and irritable bowel syndrome), thyroid dysfunction and pain (interstitial cystitis, fibromyalgia, temporomandibular joint disorder, and vulvar pain) disorders were collected. The percentage of subjects self-reporting each comorbidity was compared with the published prevalence in the general population using a single-value binomial test.
resultsSubject demographics (data presented as median [range] or percentage): age, 56.4 years (20.0-92.5); body mass index, 27.5 kg/m2 (17.4-53.1); parity 2 (0-10); white, 92.9%; and biopsy proven 65.6%. Prevalences of self-reported comorbidities in our subjects are as follows: OAB, 15.3%; UI, 38.6%; stress UI, 27.9%; inflammatory bowel diseases, 1.9%; constipation, 32.5%; irritable bowel syndrome, 19.5%; thyroid dysfunction, 33.1%; interstitial cystitis, 2.6%; fibromyalgia, 9.1%; temporomandibular joint disorder, 13.0%; and vulvar pain, 83.1%. The prevalence of each disorder is significantly different from that in the general population, with all p values ≤ .02.
conclusionsVulvar lichen sclerosus is associated with numerous bladder, bowel, and pain comorbidities. The prevalences of all of these disorders are higher in our subjects than the general population except OAB, which we find at approximately one third of the general population. Patients with lichen sclerosus should be screened for comorbidities that may affect their health and/or quality of life.
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Registered trials
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