ArticleProceedings of the National Academy of Sciences of the United States of America2012
Positional cloning and characterization reveal the molecular basis for soybean maturity locus E1 that regulates photoperiodic flowering.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 251 papers.
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Who cites it
251 citing papers in PubMed.
- FvGI-FvCO-FvFT1 pathway activates FvTFL1 in long days to repress flowering in woodland strawberry (Fragaria vesca).The New phytologist · 2026Article
- Antagonistic chromatin regulation of LHY homologs by GmASH2R and GmNF-YC4 fine-tunes soybean flowering time for latitudinal adaptation.Plant communications · 2026Article
- Genome-wide association study of diverse soybean [Glycine max (L.) Merrill] accessions for agronomic and seed composition traits in Rwanda.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Beyond the CO-FT regulatory module: E1 and PHYA emerge as players in photoperiodic regulation of flowering in legumes.Journal of experimental botany · 2026Review
- Multi-Season Multi-Model GWAS Prioritizes Stable Genomic Loci and Candidate Genes for Six Agronomic Traits in Soybean Under Conditions in Southeastern Kazakhstan.Plants (Basel, Switzerland) · 2026Article
- A combination of QTL mapping and genome‑wide association study revealed the key gene for the growth period traits in soybean.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Korean Soybean Nested Association Mapping (K-SoyNAM) population: genetic linkage map, genetic mapping, and genotype imputation.BMC genomics · 2026Article
- Quantitative trait loci analysis identifying novel genomic regions for off-target dicamba tolerance in soybean [Glycine max (L.) Merr.].BMC plant biology · 2026Article
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- Fine mapping and candidate gene analysis of a major QTL qHSW_11 for seed weight in soybean.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
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- Loss-of-function allele of the soybean flowering/maturation gene TOF11 increases free amino acid content at the edamame stage and improves eating quality.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- The current state of Japanese soybean breeding using DNA marker technology.Breeding science · 2026Article
- Molecular polymorphisms that underlie trait variation in crops: Lessons learned from soybean.The plant genome · 2026Review
- GViT-GP: injecting the genomic relationship matrix as an inductive bias into a vision transformer via cross-attention for genomic prediction.Frontiers in genetics · 2026Article
- CRISPR/Cas9 in soybean research: a measured leap toward genetic refinement.Frontiers in genome editing · 2026Review
- Genome-wide association study reveals novel genomic regions for flowering time and growth habit in cowpea (Vigna unguiculata [L.] Walp).BMC genomics · 2025Article
- Dissecting genetic architecture of flowering and maturity traits in soybean using GWAS in Indian environment.BMC plant biology · 2025Article
- Identification and field validation of QTLs for soybean red crown rot resistance from wild soybean accessions.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Dissecting seed composition QTL from wild soybean: fine-mapping, candidate gene identification, and evaluation of introgression effects on agronomic performance.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
191 more citing papers are in PubMed but not listed here.
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13 authors.
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Abstract
The complex and coordinated regulation of flowering has high ecological and agricultural significance. The maturity locus E1 has a large impact on flowering time in soybean, but the molecular basis for the E1 locus is largely unknown. Through positional cloning, we delimited the E1 locus to a 17.4-kb region containing an intron-free gene (E1). The E1 protein contains a putative bipartite nuclear localization signal and a region distantly related to B3 domain. In the recessive allele, a nonsynonymous substitution occurred in the putative nuclear localization signal, leading to the loss of localization specificity of the E1 protein and earlier flowering. The early-flowering phenotype was consistently observed in three ethylmethanesulfonate-induced mutants and two natural mutations that harbored a premature stop codon or a deletion of the entire E1 gene. E1 expression was significantly suppressed under short-day conditions and showed a bimodal diurnal pattern under long-day conditions, suggesting its response to photoperiod and its dominant effect induced by long day length. When a functional E1 gene was transformed into the early-flowering cultivar Kariyutaka with low E1 expression, transgenic plants carrying exogenous E1 displayed late flowering. Furthermore, the transcript abundance of E1 was negatively correlated with that of GmFT2a and GmFT5a, homologues of FLOWERING LOCUS T that promote flowering. These findings demonstrated the key role of E1 in repressing flowering and delaying maturity in soybean. The molecular identification of the maturity locus E1 will contribute to our understanding of the molecular mechanisms by which a short-day plant regulates flowering time and maturity.
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