Evidence map›Paper›PMID 22618964›Full record

ArticleMagnetic resonance in medicine2013

Soft constraints in nonlinear spectral fitting with regularized lineshape deconvolution.

Yan Zhang, Jun Shen

Open access · bronzeAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Effects of noise and linewidth on in vivo analysis of glutamate at 3 T.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Yan ZhangMR Spectroscopy Core Facility, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892-1527, USA. zhangya@mail.nih.gov
Jun Shen
National Institute of Mental Health · CZNational Institutes of Health · US

Funding

Magnetic Resonance Spectroscopy and Imaging Studies of Brain FunctionsZIAMH002803 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI SHEN, JUN · 2009 to 2025
$24.9M
Magnetic Resonance Spectroscopy Core FacilityZICMH002894 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI SHEN, JUN · 2009 to 2024
$13.5M
Intramural NIH HHS ZIC MH002894
6 · The paper itself

Abstract

This article presents a novel method for incorporating a priori knowledge into regularized nonlinear spectral fitting as soft constraints. Regularization was recently introduced to lineshape deconvolution as a method for correcting spectral distortions. Here, the deconvoluted lineshape was described by a new type of lineshape model and applied to spectral fitting. The nonlinear spectral fitting was carried out in two steps that were subject to hard constraints and soft constraints, respectively. The hard constraints step provided a starting point and, therefore, only the changes of the relevant variables were constrained in the soft constraints step and incorporated into the linear substeps of the Levenberg-Marquardt algorithm. The method was demonstrated using localized averaged echo time point resolved spectroscopy proton spectroscopy of human brains.

Indexed as

AlgorithmsBrain ChemistryNumerical Analysis, Computer-AssistedHumansMagnetic Resonance SpectroscopyNonlinear DynamicsProtonsProtons

Identifiers

PMID22618964
PMCPMC3432296
OpenAlexW1835529134

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.