Trial reportAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine2012
Moderation and mediation of an effective HIV risk-reduction intervention for South African adolescents.
Trial report in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00559403 (South African Adolescent Health Promotion Project), which is not on this map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
South African Adolescent Health Promotion Project
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- A Systematic Review of Randomized Controlled Trials of School Based Interventions on Sexual Risk Behaviors and Sexually Transmitted Infections Among Young Adolescents in Sub-Saharan Africa.AIDS and behavior · 2021Pooled it
- Sexual risk reduction interventions for HIV prevention among South African youth: a meta-analytic review.Current HIV research · 2013Pooled it
- Incorporation of Social Determinants of Health in the Peer-Reviewed Literature: A Systematic Review of Articles Authored by the National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention.Public health reports (Washington, D.C. : 1974)Pooled it
- Mediating Pathways in Faith-Based Sexual Risk-Reduction for African American Adolescents: Insights from a Church-Based Randomized Controlled Trial.Journal of racial and ethnic health disparities · 2026Trial
- Assessing Mediation and Moderation of an Efficacious Physical Activity Intervention for African American Men Living with HIV: The Influence of Self-Efficacy in Behavior Change.AIDS and behavior · 2026Trial
- Using Novel Approaches to Evaluate Behavioral Interventions: Overlooked Significant HIV Prevention Effects in the HPTN 015 Project EXPLORE.Journal of acquired immune deficiency syndromes (1999) · 2021Trial
- Effect of a Behavioral Intervention on Perpetrating and Experiencing Forced Sex Among South African Adolescents: A Secondary Analysis of a Cluster Randomized Trial.JAMA network open · 2018Trial
- On the Efficacy and Mediation of a One-on-One HIV Risk-Reduction Intervention for African American Men Who Have Sex with Men: A Randomized Controlled Trial.AIDS and behavior · 2015Trial
- HIV/STI risk-reduction intervention efficacy with South African adolescents over 54 months.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2015Trial
- 'Let Us Protect Our Future' a culturally congruent evidenced-based HIV/STD risk-reduction intervention for young South African adolescents.Health education research · 2014Trial
- 'Those sessions open[ed] our eyes and our minds': participant acceptability and satisfaction with a gender-focused HIV and substance use risk-reduction intervention on alcohol use, HIV treatment, and sexual behaviour among women in South Africa.Health education research · 2025Article
- Strong Father-Child Relationships and Other Positive Childhood Experiences, Adverse Childhood Experiences, and Sexual Risk Factors for HIV among Young Adults Aged 19-24 Years, Namibia, 2019: A Cross-Sectional Study.International journal of environmental research and public health · 2023Article
- Evidence and gap map report: Social and Behavior Change Communication (SBCC) interventions for strengthening HIV prevention and research among adolescent girls and young women (AGYW) in low- and middle-income countries (LMICs).Campbell systematic reviews · 2023Article
- Family Functioning in Hispanic Parents of Adolescents: Who Benefits Most from a Family-Based HIV and Substance Use Preventive Intervention?Prevention science : the official journal of the Society for Prevention Research · 2023Article
- Perceptions of peer contraceptive use and its influence on contraceptive method use and choice among young women and men in Kenya: a quantitative cross-sectional study.Reproductive health · 2022Article
- The Effects of Three Types of Sexual Orientation Victimization on HIV Sexual Risk Behavior Among Black South African Men Who Have Sex With Men (MSM).Journal of homosexuality · 2020Article
- A combination intervention addressing sexual risk-taking behaviors among vulnerable women in Uganda: study protocol for a cluster randomized clinical trial.BMC women's health · 2019Article
- What's In an Identity Label? Correlates of Sociodemographics, Psychosocial Characteristics, and Sexual Behavior Among African American Men Who Have Sex With Men.Archives of sexual behavior · 2018Article
- Childhood Sexual Abuse and Sociodemographic Factors Prospectively Associated with Intimate Partner Violence Perpetration Among South African Heterosexual Men.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2017Article
- Mediation and moderation of an efficacious theory-based abstinence-only intervention for African American adolescents.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2015Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
background"Let Us Protect Our Future" is a sexual risk-reduction intervention for sixth-grade adolescents in South Africa. Tested in a cluster-randomized controlled trial, the intervention significantly reduced self-reported intercourse and unprotected intercourse during a 12-month follow-up period. PURPOSE: The present analyses were conducted to identify moderators of the intervention's efficacy as well as, which theory-based variables mediated the intervention's effects.
methodsIntervention efficacy over the 3-, 6-, and 12-month follow-up was tested using generalized estimating equation models.
resultsLiving with their father in the home, parental strictness, and religiosity moderated the efficacy of the intervention in reducing unprotected intercourse. Self-efficacy to avoid risky situations and expected parental disapproval of their having intercourse, derived from Social Cognitive Theory, significantly mediated the intervention's effect on abstinence.
conclusionsThis is the first study to demonstrate that Social Cognitive variables mediate the efficacy of a sexual risk-reduction intervention among South African adolescents.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.