ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2012
Comparison of biometrical approaches for QTL detection in multiple segregating families.
Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Mapping quantitative trait loci for biomass yield and yield-related traits in lowland switchgrass (Panicum virgatum L.) multiple populations.G3 (Bethesda, Md.) · 2023Article
- Multiallelic models for QTL mapping in diverse polyploid populations.BMC bioinformatics · 2022Article
- Drought Resistance in Rice from Conventional to Molecular Breeding: A Review.International journal of molecular sciences · 2019Review
- Improvement of Drought Tolerance in Rice (BioMed research international · 2018Review
- How do the type of QTL effect and the form of the residual term influence QTL detection in multi-parent populations? A case study in the maize EU-NAM population.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2017Article
- Predicting Flowering Behavior and Exploring Its Genetic Determinism in an Apple Multi-family Population Based on Statistical Indices and Simplified Phenotyping.Frontiers in plant science · 2017Article
- Genetic control of protein content and sedimentation volume in European winter wheat cultivars.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2016Article
- Detecting QTLs and putative candidate genes involved in budbreak and flowering time in an apple multiparental population.Journal of experimental botany · 2016Article
- QTL mapping of carrot resistance to leaf blight with connected populations: stability across years and consequences for breeding.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2015Article
- Genetic control of plant height in European winter wheat cultivars.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2015Article
- Article
- Adult plant development in triticale (× triticosecale wittmack) is controlled by dynamic genetic patterns of regulation.G3 (Bethesda, Md.) · 2014Article
- Genetic dynamics underlying phenotypic development of biomass yield in triticale.BMC genomics · 2014Article
- Mapping dynamic QTL for plant height in triticale.BMC genetics · 2014Article
- Flowering time control in European winter wheat.Frontiers in plant science · 2014Article
- Multiple-line cross QTL mapping for biomass yield and plant height in triticale (× Triticosecale Wittmack).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2014Article
- Article
- Combined linkage and linkage disequilibrium QTL mapping in multiple families of maize (Zea mays L.) line crosses highlights complementarities between models based on parental haplotype and single locus polymorphism.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2013Article
- High-density genotyping: an overkill for QTL mapping? Lessons learned from a case study in maize and simulations.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2013Article
- Optimum design of family structure and allocation of resources in association mapping with lines from multiple crosses.Heredity · 2013Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Detection of QTL in multiple segregating families possesses many advantages over the classical QTL mapping in biparental populations. It has thus become increasingly popular, and different biometrical approaches are available to analyze such data sets. We empirically compared an approach based on linkage mapping methodology with an association mapping approach. To this end, we used a large population of 788 elite maize lines derived from six biparental families genotyped with 857 SNP markers. In addition, we constructed genetic maps with reduced marker densities to assess the dependency of the performance of both mapping approaches on the marker density. We used cross-validation and resample model averaging and found that while association mapping performed better under high marker densities, this was reversed under low marker densities. In addition to main effect QTL, we also detected epistatic interactions. Our results suggest that both approaches will profit from a further increase in marker density and that a cross-validation should be applied irrespective of the biometrical approach.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.