ReviewDer Anaesthesist2012
[Postoperative cognitive dysfunction. Possible neuronal mechanisms and practical consequences for clinical routine].
Review in Der Anaesthesist, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 12 citations in OpenAlex.
- Perioperative neurocognitive functions in patients with neuroepithelial intracranial tumors.Journal of neuro-oncology · 2020Trial
- Preoperative cognitive intervention reduces cognitive dysfunction in elderly patients after gastrointestinal surgery: a randomized controlled trial.Medical science monitor : international medical journal of experimental and clinical research · 2015Trial
- Analysis of Determinants and Development of a Predictive Model for Postoperative Cognitive Dysfunction in Patients Undergoing Hepatectomy.Journal of clinical medicine · 2026Article
- Biomechanical comparison of acetabular fracture fixation with stand-alone THA or in combination with plating.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Article
- Intracisternal administration of an interleukin-6 receptor antagonist attenuates surgery-induced cognitive impairment by inhibition of neuroinflammatory responses in aged rats.Experimental and therapeutic medicine · 2015Article
- Protective effect of senegenin on splenectomy-induced postoperative cognitive dysfunction in elderly rats.Experimental and therapeutic medicine · 2014Article
- [Developmental abnormalities in children following surgery under general anesthesia: anesthesiological problem?].Der Anaesthesist · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Postoperative cognitive dysfunction (POCD) presents as a long-lasting decline in cognitive function after a surgical procedure, predominantly occurring in elderly patients. The causes are most likely multifactorial with the exact mechanisms still unknown. Hypotheses of the causes of POCD are based on experimental evidence that anesthetics can impair mechanisms of learning and memory on a neuronal level and might lead to neurodegeneration. Additionally, surgery can result in neuroinflammation which could also underlie POCD. The most important strategy to avoid POCD is to maintain the patient's physiological homeostasis perioperatively. According to the presently available clinical studies recommendations in favor or against certain anesthesiological procedures cannot be given.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.