ArticleLasers in medical science2013
Quantitative measurement of optical attenuation coefficients of cell lines CNE1, CNE2, and NP69 using optical coherence tomography.
Article in Lasers in medical science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 13 citations in OpenAlex.
- The NRF2/KEAP1 Pathway Modulates Nasopharyngeal Carcinoma Cell Radiosensitivity via ROS Elimination.OncoTargets and therapy · 2020Article
- miR-193a-3p Promotes Radio-Resistance of Nasopharyngeal Cancer Cells by Targeting SRSF2 Gene and Hypoxia Signaling Pathway.Medical science monitor basic research · 2019Article
- Protocadherin 17 is a tumor suppressor and is frequently methylated in nasopharyngeal carcinoma.Cancer management and research · 2019Article
- MiR-20a-5p promotes radio-resistance by targeting NPAS2 in nasopharyngeal cancer cells.Oncotarget · 2017Article
- MiR-20a-5p promotes radio-resistance by targeting Rab27B in nasopharyngeal cancer cells.Cancer cell international · 2017Article
- Automated, Depth-Resolved Estimation of the Attenuation Coefficient From Optical Coherence Tomography Data.IEEE transactions on medical imaging · 2015Article
- Depth-resolved model-based reconstruction of attenuation coefficients in optical coherence tomography.Biomedical optics express · 2013Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
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Abstract
The radiotherapy-related types of nasopharyngeal carcinoma (NPC) have been established, which give the most effective treatment for NPC patients using the individual therapy. To diagnose the types of NPC, we assess the general NPC cell lines CNE1, CNE2 and normal nasopharyngeal cell line NP69 using optical coherence tomography (OCT) in two steps: firstly, the OCT images of the three different types of cell pellets are captured. Secondly, by fitting Beer's law to the averaged A-scans in these OCT datasets, the attenuation coefficients (μ t ) of the cells can be extracted. The median attenuation coefficients (interquartile range) of CNE1, CNE2, and NP69 are 5.58 mm(-1) (IQR 5.55 to 5.65 mm(-1)), 5.91 mm(-1) (IQR 5.82 to 5.88 mm(-1)), and 8.96 mm(-1) (IQR 8.80 to 9.47 mm(-1)), respectively. The distinguishable quantitative OCT analysis (by μ t ) shows that the types of NPC could potentially be differentiated in real time and noninvasive.
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