ArticleEuropean journal of clinical nutrition2012
Dietary fibre intake and ischaemic heart disease mortality: the European Prospective Investigation into Cancer and Nutrition-Heart study.
Article in European journal of clinical nutrition, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Dietary intake of total vegetable, fruit, cereal, soluble and insoluble fiber and risk of all-cause, cardiovascular, and cancer mortality: systematic review and dose-response meta-analysis of prospective cohort studies.Frontiers in nutrition · 2023Pooled it
- Associations between dietary fiber intake and cardiovascular risk factors: An umbrella review of meta-analyses of randomized controlled trials.Frontiers in nutrition · 2022Pooled it
- Dietary fibre intake and risk of cardiovascular disease: systematic review and meta-analysis.BMJ (Clinical research ed.) · 2013Pooled it
- Trial
- Propionate attenuates atherosclerosis by immune-dependent regulation of intestinal cholesterol metabolism.European heart journal · 2022Trial
- A global analysis of the burden of ischemic heart disease attributable to diet low in fiber between 1990 and 2019.BMC cardiovascular disorders · 2024Article
- Incremental monounsaturated to saturated fat ratio and fibre consumption is associated with a reduction in a composite score of modifiable cardiovascular risk factors: Prospective results from the Moli-sani study.European journal of clinical nutrition · 2022Article
- Association of Dietary Fiber Intake With Myocardial Infarction and Stroke Events in US Adults: A Cross-Sectional Study of NHANES 2011-2018.Frontiers in nutrition · 2022Article
- Burden and trend of ischemic heart disease and colorectal cancer attributable to a diet low in fiber in China, 1990-2017: findings from the Global Burden of Disease Study 2017.European journal of nutrition · 2021Article
- Risks of ischaemic heart disease and stroke in meat eaters, fish eaters, and vegetarians over 18 years of follow-up: results from the prospective EPIC-Oxford study.BMJ (Clinical research ed.) · 2019Article
- Dietary Fiber, Atherosclerosis, and Cardiovascular Disease.Nutrients · 2019Review
- Dietary intake of patients with angiographically defined coronary artery disease and that of healthy controls in Iran.European journal of clinical nutrition · 2014Article
- Article
- Dietary fibre and cardiovascular disease mortality in the UK Women's Cohort Study.European journal of epidemiology · 2013Article
Corrections and comments
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Authors and funding
40 authors at 20 institutions in 9 countries.
Funding
Abstract
BACKGROUND/
objectivesEvidence from prospective studies is consistent in showing an inverse association between dietary fibre intake and risk of ischaemic heart disease (IHD), but whether dietary fibre from various food sources differ in their effect on IHD risk is less clear. The objective of this study was to assess the associations of total and food sources of dietary fibre with IHD mortality in the European Prospective Investigation into Cancer and Nutrition-Heart study. SUBJECTS/
methodsParticipants were 306,331 men and women from eight European countries. Dietary fibre intake was assessed using centre or country-specific diet questionnaires and calibrated using a 24-h diet recall.
resultsAfter an average follow-up of 11.5 years, there were 2381 IHD deaths among participants without cardiovascular disease at baseline. The calibrated intake of dietary fibre was inversely related with IHD mortality; each 10 g/day was associated with a 15% lower risk (relative risk (RR) 0.85; 95% confidence interval (CI): 0.73-0.99, P=0.031). There was no difference in the associations of the individual food sources of dietary fibre with the risk of IHD mortality; RR for each 5 g/day higher cereal fibre intake was 0.91 (CI: 0.82-1.01), RR for each 2.5 g/day fruit fibre intake was 0.94 (CI: 0.88-1.01) and RR for each 2.5 g/day vegetable fibre intake was 0.90 (95% CI: 0.76-1.07).
conclusionA higher consumption of dietary fibre is associated with a lower risk of fatal IHD with no clear difference in the association with IHD for fibre from cereals, fruits or vegetables.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.