ArticleACS nano2012
Development of iron-doped silicon nanoparticles as bimodal imaging agents.
Article in ACS nano, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Laser-Ablative Synthesis of Silicon-Iron Composite Nanoparticles for Theranostic Applications.Nanomaterials (Basel, Switzerland) · 2023Article
- Gadolinium-doped fluorescent carbon quantum dots as MRI contrast agents and fluorescent probes.Scientific reports · 2022Article
- The In Vivo Toxicity Assessments of Water-Dispersed Fluorescent Silicon Nanoparticles inInternational journal of environmental research and public health · 2022Article
- Synthesis of Magnetic Ions-Doped QDs Synthesized Via a Facial Aqueous Solution Method for Optical/MR Dual-Modality Imaging Applications.Journal of fluorescence · 2021Article
- Zintl Phases as Reactive Precursors for Synthesis of Novel Silicon and Germanium-Based Materials.Materials (Basel, Switzerland) · 2019Review
- Nanometer size silicon particles for hyperpolarized MRI.Scientific reports · 2017Article
- Design and Synthesis of New Sulfur-Containing Hyperbranched Polymer and Theranostic Nanomaterials for Bimodal Imaging and Treatment of Cancer.ACS macro letters · 2017Article
- EPR and Structural Characterization of Water-Soluble MnThe journal of physical chemistry. C, Nanomaterials and interfaces · 2017Article
- Zwitterionic amphiphile coated magnetofluorescent nanoparticles - synthesis, characterization and tumor cell targeting.Journal of materials chemistry. B · 2015Article
- Synthesis of long T₁ silicon nanoparticles for hyperpolarized ²⁹Si magnetic resonance imaging.ACS nano · 2013Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
We demonstrate the synthesis of water-soluble allylamine-terminated Fe-doped Si (Si(xFe)) nanoparticles as bimodal agents for optical and magnetic imaging. The preparation involves the synthesis of a single-source iron-containing precursor, Na(4)Si(4) with x% Fe (x = 1, 5, 10), and its subsequent reaction with NH(4)Br to produce hydrogen-terminated Si(xFe) nanoparticles. The hydrogen-capped nanoparticles are further terminated with allylamine via thermal hydrosilylation. Transmission electron microscopy indicates that the average particle diameter is ∼3.0 ± 1.0 nm. The Si(5Fe) nanoparticles show strong photoluminescence quantum yield in water (∼10%) with significant T(2) contrast (r(2)/r(1) value of 4.31). Electron paramagnetic resonance and Mössbauer spectroscopies indicate that iron in the nanoparticles is in the +3 oxidation state. Analysis of cytotoxicity using the resazurin assay on HepG2 liver cells indicates that the particles have minimal toxicity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.