ArticlePloS one2012
Identification of genes related to white and black plumage formation by RNA-Seq from white and black feather bulbs in ducks.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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Who cites it
50 citing papers in PubMed, 107 citations in OpenAlex.
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- Development and Characterization of a Single Nucleotide Polymorphism Genotyping Panel for Duck Populations.Animals : an open access journal from MDPI · 2026Article
- Melanin Deposition and Screening of Melanogenesis-Related Differential RNAs and Construction of ceRNA Regulatory Network in Liancheng White Ducks.Animals : an open access journal from MDPI · 2026Article
- Potential Genetic Markers Associated with Coloration in Duck: A Review.International journal of molecular sciences · 2025Review
- Effects ofJournal of animal science and technology · 2025Article
- A high-quality assembly revealing the PMEL gene for the unique plumage phenotype in Liancheng ducks.GigaScience · 2025Article
- Regulatory gene network for coffee-like color morph of TYRP1 mutant of oujiang color common carp.BMC genomics · 2024Article
- Transcriptome analysis of sexual dimorphism in dorsal down coloration in goslings.BMC genomics · 2024Article
- Identification of Differentially Expressed Genes and microRNAs in the Gray and White Feather Follicles of Shitou Geese.Animals : an open access journal from MDPI · 2024Article
- Investigation into the association ofOpen life sciences · 2024Article
- Genome-Wide Association Studies Reveal Candidate Genes Associated with Pigmentation Patterns of Single Feathers of Tianfu Nonghua Ducks.Animals : an open access journal from MDPI · 2023Article
- The draft genome of the Temminck's tragopan (Tragopan temminckii) with evolutionary implications.BMC genomics · 2023Article
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- Coordinated microRNA/mRNA Expression Profiles Reveal Unique Skin Color Regulatory Mechanisms in Chinese Giant Salamander (Animals : an open access journal from MDPI · 2023Article
- Association analysis of melanophilin (Archives animal breeding · 2023Article
- Genome-wide association study for the primary feather color trait in a native Chinese duck.Frontiers in genetics · 2023Article
- Draft genome assemblies of four manakins.Scientific data · 2022Article
- The evolutionary history and mechanistic basis of female ornamentation in a tropical songbird.Evolution; international journal of organic evolution · 2022Article
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Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To elucidate the genes involved in the formation of white and black plumage in ducks, RNA from white and black feather bulbs of an F(2) population were analyzed using RNA-Seq. A total of 2,642 expressed sequence tags showed significant differential expression between white and black feather bulbs. Among these tags, 186 matched 133 annotated genes that grouped into 94 pathways. A number of genes controlling melanogenesis showed differential expression between the two types of feather bulbs. This differential expression was confirmed by qPCR analysis and demonstrated that Tyr (Tyrosinase) and Tyrp1 (Tyrosinase-related protein-1) were expressed not in W-W (white feather bulb from white dorsal plumage) and W-WB (white feather bulb from white-black dorsal plumage) but in B-B (black feather bulb from black dorsal plumage) and B-WB (black feather bulb from white-black dorsal plumage) feather bulbs. Tyrp2 (Tyrosinase-related protein-2) gene did not show expression in the four types of feather bulbs but expressed in retina. C-kit (The tyrosine kinase receptor) expressed in all of the samples but the relative mRNA expression in B-B or B-WB was approximately 10 fold higher than that in W-W or W-WB. Additionally, only one of the two Mitf isoforms was associated with plumage color determination. Downregulation of c-Kit and Mitf in feather bulbs may be the cause of white plumage in the duck.
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