Evidence map›Paper›PMID 22615715›Full record

ArticleF1000 biology reports2012

The immune diet: meeting the metabolic demands of lymphocyte activation.

Ruoning Wang, Douglas R Green

Open access · bronzeAbstract read
In one paragraph

Article in F1000 biology reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
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  4. Pyruvate Kinase M2: a Metabolic Bug in Re-Wiring the Tumor Microenvironment.Cancer microenvironment : official journal of the International Cancer Microenvironment Society · 2019
    Review
  5. A Metabolism Toolbox for CAR T Therapy.Frontiers in oncology · 2019
    Review
  6. Review
  7. Review
  8. Review
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  11. Review
  12. Review
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  14. Metabolic control of the Treg/Th17 axis.Immunological reviews · 2013
    Review
  15. Article
  16. Review
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  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ruoning WangDepartment of Immunology, St. Jude Children's Research Institute Memphis, TN USA.
Douglas R Green
St. Jude Children's Research Hospital · US

Funding

Non-canonical functions of autophagy proteinsR01AI040646 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI GREEN, DOUGLAS R. · 1997 to 2023
$8.6M
Mechanisms of Stress Induced Apoptosis in T-CellsR37GM052735 · NIGMS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI GREEN, DOUGLAS R. · 2002 to 2011
$4.1M
MECHANISMS OF STRESS-INDUCED APOPTOSIS IN T CELLSR01GM052735 · NIGMS · LA JOLLA INST FOR ALLERGY &IMMUNOLGY · PI GREEN, DOUGLAS R · 1994 to 2001
$594k
NIAID NIH HHS R01 AI040646NIGMS NIH HHS R01 GM052735NIGMS NIH HHS R37 GM052735
6 · The paper itself

Abstract

During the adaptive immune response, lymphocytes undergo dramatic changes in metabolism that accompany the proliferative burst and differentiation into functional subsets. This brief overview focuses on recent advances in understanding the mechanisms of this metabolic reprogramming in T lymphocytes.

Identifiers

PMID22615715
PMCPMC3342832
OpenAlexW2120538932

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.