Evidence map›Paper›PMID 22614518›Full record

ArticleIEEE transactions on bio-medical engineering2012

A preclinical system prototype for focused microwave thermal therapy of the breast.

John Stang, Mark Haynes, Paul Carson, Mahta Moghaddam

Open access · greenAbstract read
In one paragraph

Article in IEEE transactions on bio-medical engineering, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 142 citations in OpenAlex.

  1. Review
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  10. Nanotechnology for colorectal cancer detection and treatment.World journal of gastroenterology · 2022
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Microwave Sensors for Breast Cancer Detection.Sensors (Basel, Switzerland) · 2018
    Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

John StangDepartment of Electrical Engineering and Computer Science, The University of Michigan, Ann Arbor, MI 48109-2122, USA. john.stang@gmail.com
Mark Haynes
Paul Carson
Mahta Moghaddam
University of Michigan–Ann Arbor · US

Funding

Training Future Imaging Scientists for BiomedicineT32EB005172 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FOWLKES, JEFFREY B · 2008 to 2012
$1.1M
NIBIB NIH HHS T32 EB005172
6 · The paper itself

Abstract

A preclinical prototype of a transcutaneous thermal therapy system has been developed for the targeted treatment of breast cancer cells using focused microwaves as an adjuvant to radiation, chemotherapy, and high-intensity-focused ultrasound. The prototype system employs a 2-D array of tapered microstrip patch antennas operating at 915 MHz to focus continuous-wave microwave energy transcutaneously into the pendent breast suspended in a coupling medium. Prior imaging studies are used to ascertain the material properties of the breast tissue, and these data are incorporated into a multiphysics model. Time-reversal techniques are employed to find a solution (relative amplitudes and phase) for focusing at a given location. Modeling tests of this time-reversal focusing method have been performed, which demonstrate good targeting accuracy within heterogeneous breast tissue. Experimental results using the laboratory prototype to perform focused heating in tissue-mimicking gelatin phantoms have demonstrated 1.5-cm-diameter focal spot sizes and differential heating at the desired focus sufficient to achieve an antitumor effect confined to the target region.

Indexed as

Models, TheoreticalPhantoms, ImagingBreast NeoplasmsEquipment DesignFemaleHumansHyperthermia, InducedImage Processing, Computer-AssistedMicrowaves

Identifiers

PMID22614518
PMCPMC5010918
OpenAlexW2169161417

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.