ReviewNature reviews. Urology2012
MicroRNAs as putative mediators of treatment response in prostate cancer.
Review in Nature reviews. Urology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Using microRNAs as Novel Predictors of Urologic Cancer Survival: An Integrated Analysis.EBioMedicine · 2018Pooled it
- Potential Regulation of miRNA-29 and miRNA-9 by Estrogens in Neurodegenerative Disorders: An Insightful Perspective.Brain sciences · 2023Review
- Investigating the Function of MicroRNAs in Human Retinal Microvascular Endothelial Cells of Diabetic Retinopathy.Methods in molecular biology (Clifton, N.J.) · 2023Article
- MicroRNA-29b-3p Promotes Human Retinal Microvascular Endothelial Cell Apoptosis via Blocking SIRT1 in Diabetic Retinopathy.Frontiers in physiology · 2019Article
- MicroRNAs Associated with Von Hippel-Lindau Pathway in Renal Cell Carcinoma: A Comprehensive Review.International journal of molecular sciences · 2017Review
- Gene suppression approaches to neurodegeneration.Alzheimer's research & therapy · 2017Review
- A prognostic model for lung adenocarcinoma patient survival with a focus on four miRNAs.Oncology letters · 2017Article
- Downregulation of miR-130b~301b cluster is mediated by aberrant promoter methylation and impairs cellular senescence in prostate cancer.Journal of hematology & oncology · 2017Article
- Profiling of a panel of radioresistant prostate cancer cells identifies deregulation of key miRNAs.Clinical and translational radiation oncology · 2017Article
- MiR-124 enhances cell radiosensitivity by targeting PDCD6 in nasopharyngeal carcinoma.International journal of clinical and experimental pathology · 2017Article
- When Prostate Cancer Circulates in the Bloodstream.Diagnostics (Basel, Switzerland) · 2015Review
- MiR-23a sensitizes nasopharyngeal carcinoma to irradiation by targeting IL-8/Stat3 pathway.Oncotarget · 2015Article
- Role of microRNA in response to ionizing radiations: evidences and potential impact on clinical practice for radiotherapy.Molecules (Basel, Switzerland) · 2014Review
- Article
- Involvement of miR-20a in promoting gastric cancer progression by targeting early growth response 2 (EGR2).International journal of molecular sciences · 2013Article
- Aberrant expression of microRNAs in bladder cancer.Nature reviews. Urology · 2013Review
- The genomic landscape of prostate cancer.International journal of molecular sciences · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MicroRNAs (miRNAs) are an abundant class of noncoding RNAs that function to regulate post-transcriptional gene expression, predominantly by translational repression. In addition to their role in prostate cancer initiation and progression, recent evidence suggests that miRNAs might also participate in treatment response across a range of therapies including radiation treatment, chemotherapy and androgen suppression. The mechanism of this regulation is thought to be multifactorial and is currently poorly understood. To date, only a small number of studies have examined the functional role of miRNAs in response to prostate cancer treatment. Elucidating the role of miRNAs in treatment response following radiotherapy, chemotherapy and androgen suppression will provide new avenues of investigation for the development of novel therapies for the treatment of prostate cancer.
Indexed as
Identifiers
22613932What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.