Evidence map›Paper›PMID 22613331›Full record

ArticleZhongguo fei ai za zhi = Chinese journal of lung cancer2012

[Establishment and characterization of a human lung adenocarcinoma cell line, Ch-Huang-1].

Bailing Li, Keng Zhong, Lei Jin, Yang Yuan, Dejun Gong, Xiaohong Liu, Shengdong Huang

Erratum issuedAbstract readEnglish Abstract
In one paragraph

Article in Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

7 authors.

Bailing LiDepartment of Cardiothoracic Surgery, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China.
Keng Zhong
Lei Jin
Yang Yuan
Dejun Gong
Xiaohong Liu
Shengdong Huang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveLung cancer is a major worldwide health problem. The aim of this study is to establish a novel Chinese human lung adenocarcinoma cell line and examine its biological characteristics.

methodsLung adenocarcinoma specimens were freshly resected during surgery. The tissues were incubated in vitro and the cell line was named Ch-Huang-1. The biological characteristics of the cells were investigated by light microscopy, chromosome analysis, and transplantation experiment.

resultsLight microscopy revealed that cells from the primary tumor, Ch-Huang-1 cell line, and transplanted tumor possessed the characteristics of a malignant glandular epithelial tumor. The cell growth curve, doubling time, and mitotic index were also observed in vitro. Nuclear chromosome analysis revealed that the tumor was a subtriploid with a mode of 35-44 per cell. Tumor nodes were observed under the skin of nude mice by heterogenic transplantation.

conclusionThe characteristics of the established cell line suggest that it is a newly established human adenocarcinoma cell line.

Indexed as

Cell ProliferationAdenocarcinomaAnimalsCell Line, TumorChromosome AberrationsFemaleHumansKaryotypingLung NeoplasmsMiceMice, NudeMicroscopy, FluorescenceMiddle AgedNeoplasms, ExperimentalTime FactorsTransplantation, Heterologous

Identifiers

PMID22613331
PMCPMC6000122

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.