Evidence map›Paper›PMID 22613230›Full record

Trial reportBrain research2012

Fluid reasoning deficits in children with ADHD: evidence from fMRI.

Leanne Tamm, Jenifer Juranek

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Brain research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Fluid Intelligence in Children with Learning Disabilities.Psychology in Russia : state of the art · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. COMT and DAT1 polymorphisms moderate the indirect effect of parenting behavior on youth ADHD symptoms through neurocognitive functioning.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2018
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Neurocognitive Functioning Mediates the Prospective Association of Birth Weight With Youth ADHD Symptoms.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Leanne TammCincinnati Children's Hospital Medical Center, Department of Pediatrics, 3333 Burnet Avenue, MLC 10006, Cincinnati, OH 45229, USA. leanne.tamm@cchmc.org
Jenifer Juranek
Cincinnati Children's Hospital Medical Center · USThe University of Texas Health Science Center at Houston · US

Funding

NORTH AND CENTRAL TEXAS CTSA FOR PEDIATRIC RESEARCHUL1RR024982 · NCRR · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2007 to 2011
$27.9M
NCRR NIH HHS UL1 RR024982NCRR NIH HHS UL1RR024982
6 · The paper itself

Abstract

Attention-Deficit/Hyperactivity Disorder (ADHD) is associated with deficits in fluid reasoning, which may be related to self-regulation of cognition and behavior, and requires intact attention, working memory, and inhibition skills. No functional magnetic resonance imaging (fMRI) studies have directly examined fluid reasoning in ADHD which is surprising given that studies demonstrate a consistent network of brain regions involved in fluid reasoning that are also implicated in the pathogenesis of ADHD. Twenty-two right-handed, non-medicated children (12 ADHD, 10 controls) ages 8-12 years completed a fluid reasoning task during which fMRI data were collected. The primary comparison of interest was activation during the fluid reasoning compared to the control condition. Behavioral data showed that children with ADHD tended to be less accurate with faster reaction times in the fluid reasoning condition compared to controls, and were significantly less accurate in the control condition. Controls activated more than participants with ADHD in the right intraparietal sulcus and the left lateral cerebellum in the fluid reasoning condition. Results showed hypoactivation in ADHD in regions critical for fluid reasoning. These results add to the literature suggesting a role for parietal and cerebellar regions in cognition and ADHD.

Indexed as

Attention Deficit Disorder with HyperactivityCerebellumChildChild BehaviorCognition DisordersFemaleHumansMagnetic Resonance ImagingMaleMental ProcessesParietal LobePilot Projects

Identifiers

PMID22613230
PMCPMC3383331
OpenAlexW2091257595

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.