ArticleAnnals of the New York Academy of Sciences2012
The hypothalamic-pituitary-adrenal axis and sex hormones in chronic stress and obesity: pathophysiological and clinical aspects.
Article in Annals of the New York Academy of Sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
72 citing papers in PubMed, 1 synthesis or guideline pooled it, 129 citations in OpenAlex.
- Perceived stress and diet quality in women of reproductive age: a systematic review and meta-analysis.Nutrition journal · 2020Pooled it
- Community-based participatory research to design a faith-enhanced diabetes prevention program: The Better Me Within randomized trial.Contemporary clinical trials · 2017Trial
- Impact of Short-term Rehabilitation on Chronic Stress-induced Brain Alterations and Associated Cognitive Deficits.Annals of neurosciences · 2026Article
- Article
- Sex hormone-psoriasis interactions: from sex-specific clinical features to immunoregulatory mechanisms.Frontiers in immunology · 2026Review
- Psychosocial factors and the development of childhood overweight and obesity: a UK cohort study.Pediatric research · 2025Article
- Gender Differences in Social Determinants of Hypertension Among Older Brazilian Adults Residing in Urban Areas: A Multilevel Approach from the ELSI-Urbe.Journal of urban health : bulletin of the New York Academy of Medicine · 2025Article
- Biological embodiment of educational attainment and future risk of breast cancer: findings from a French prospective cohort.BMJ open · 2025Article
- Mechanistic insights regarding neuropsychiatric and neuropathologic impacts of air pollution.Critical reviews in toxicology · 2024Review
- Relationship between Ikigai and longitudinal changes in serum HDL cholesterol levels: the Circulatory Risk in Communities Study (CIRCS).Lipids in health and disease · 2024Article
- Aircraft noise exposure and body mass index among female participants in two Nurses' Health Study prospective cohorts living around 90 airports in the United States.Environment international · 2024Article
- Stress and sleep deprivation-related biomarkers in saliva in patients with retinitis pigmentosa.PloS one · 2024Observational
- Exposure to Gestational Diabetes and BMI Trajectories Through Adolescence: The Exploring Perinatal Outcomes Among Children Study.The Journal of clinical endocrinology and metabolism · 2023Article
- Associations of obesity and body shape with erythrocyte and reticulocyte parameters in the UK Biobank cohort.BMC endocrine disorders · 2023Article
- Effects of very low-calorie ketogenic diet on hypothalamic-pituitary-adrenal axis and renin-angiotensin-aldosterone system.Journal of endocrinological investigation · 2023Review
- Stressful Life Events, Unhealthy Eating Behaviors and Obesity among Chinese Government Employees: A Follow-Up Study.Nutrients · 2023Article
- Article
- Sex differences in the associations of body size and body shape with platelets in the UK Biobank cohort.Biology of sex differences · 2023Article
- Genetic analyses implicate complex links between adult testosterone levels and health and disease.Communications medicine · 2023Article
- Do any kinds of perceived stressors lead to hypertension? A longitudinal cohort study.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Article
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity, particularly the abdominal phenotype, has been ascribed to an individual maladaptation to chronic environmental stress exposure mediated by a dysregulation of related neuroendocrine axes. Alterations in the control and action of the hypothalamic-pituitary-adrenal axis play a major role in this context, with the participation of the sympathetic nervous system. The ability to adapt to chronic stress may differ according to sex, with specific pathophysiological events leading to the development of stress-related chronic diseases. This seems to be influenced by the regulatory effects of sex hormones, particularly androgens. Stress may also disrupt the control of feeding, with some differences according to sex. Finally, the amount of experimental data in both animals and humans may help to shed more light on specific phenotypes of obesity, strictly related to the chronic exposure to stress. This challenge may potentially imply a different pathophysiological perspective and, possibly, a specific treatment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.