Evidence map›Paper›PMID 22612130›Full record

ArticleJournal of biomedical optics2012

Temperature-modulated fluorescence tomography based on both concentration and lifetime contrast.

Yuting Lin, Tiffany C Kwong, Linden Bolisay, Gultekin Gulsen

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Nanomedicines for Near-Infrared Fluorescent Lifetime-Based Bioimaging.Frontiers in bioengineering and biotechnology · 2019
    Review
  9. Review
  10. Recent methodology advances in fluorescence molecular tomography.Visual computing for industry, biomedicine, and art · 2018
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yuting LinUniversity of California, Department of Radiological Sciences, Tu and Yuen Center for Functional Onco-Imaging, Irvine, CA 92697, USA. yutingl@uci.edu
Tiffany C Kwong
Linden Bolisay
Gultekin Gulsen

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Christine Hui · 1994 to 2026
$57.9M
Development of A Multi-Modality System for Onco-ImagingR33CA120175 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI GULSEN, GULTEKIN · 2008 to 2010
$1.5M
Tomographic Molecular Imaging for Breast CancerR01EB008716 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI GULSEN, GULTEKIN · 2008 to 2011
$1.3M
Development of A Multi-Modality System for Onco-ImagingR21CA120175 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI GULSEN, GULTEKIN · 2007 to 2007
$225k
NCI NIH HHS CA120175NCI NIH HHS P30 CA062203NCI NIH HHS R01CA1429898NCI NIH HHS R21 CA120175NCI NIH HHS R33 CA120175NIBIB NIH HHS R01 EB008716NIBIB NIH HHS R01EB008716
6 · The paper itself

Abstract

It is challenging to image fluorescence objects with high spatial resolution in a highly scattering medium. Recently reported temperature-sensitive indocyanine green-loaded pluronic nanocapsules can potentially alleviate this problem. Here we demonstrate a frequency-domain temperature-modulated fluorescence tomography system that could acquire images at high intensity-focused ultrasound resolution with use of these nanocapsules. The system is experimentally verified with a phantom study, where a 3-mm fluorescence object embedded 2 cm deep in a turbid medium is successfully recovered based on both intensity and lifetime contrast.

Indexed as

Indocyanine GreenNanocapsulesContrast MediaImage EnhancementMicroscopy, FluorescencePhantoms, ImagingReproducibility of ResultsSensitivity and SpecificityTemperatureTomography, OpticalContrast MediaIndocyanine GreenNanocapsules

Identifiers

PMID22612130
PMCPMC3381013

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.