Evidence map›Paper›PMID 22610698›Full record

ReviewAdvanced materials (Deerfield Beach, Fla.)2012

Hybrid nanoparticles for detection and treatment of cancer.

Michael J Sailor, Ji-Ho Park

Abstract readReview
In one paragraph

Review in Advanced materials (Deerfield Beach, Fla.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed.

  1. TargetedJournal of nanobiotechnology · 2026
    Article
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  13. Putting Hybrid Nanomaterials to Work for Biomedical Applications.Angewandte Chemie (International ed. in English) · 2024
    Review
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  15. Article
  16. Review
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  18. Article
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38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael J SailorMaterials Science and Engineering Program, Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman, La Jolla, CA 92093, USA. msailor@ucsd.edu
Ji-Ho Park

Funding

Engineering Multifunctional NanoparticlesR01CA124427 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BHATIA, SANGEETA N. · 2006 to 2010
$4.7M
NCI NIH HHS R01 CA124427NCI NIH HHS R01CA124427-01
6 · The paper itself

Abstract

There is currently considerable effort to incorporate both diagnostic and therapeutic functions into a single nanoscale system for the more effective treatment of cancer. Nanoparticles have great potential to achieve such dual functions, particularly if more than one type of nanostructure can be incorporated in a nanoassembly, referred to in this review as a hybrid nanoparticle. Here we review recent developments in the synthesis and evaluation of such hybrid nanoparticles based on two design strategies (barge vs. tanker), in which liposomal, micellar, porous silica, polymeric, viral, noble metal, and nanotube systems are incorporated either within (barge) or at the surface of (tanker) a nanoparticle. We highlight the design factors that should be considered to obtain effective nanodevices for cancer detection and treatment.

Indexed as

AnimalsBiocompatible MaterialsHumansMaterials TestingNanoconjugatesNanoparticlesNanotechnologyNeoplasmsBiocompatible MaterialsNanoconjugates

Identifiers

PMID22610698
PMCPMC3517011

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.