ArticleHuman brain mapping2013
Learning-dependent plasticity in human auditory cortex during appetitive operant conditioning.
Article in Human brain mapping, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Trial
- Psilocybin Attenuates Cortical Representations of Aversion in the Mouse Auditory Cortex.bioRxiv : the preprint server for biology · 2026Article
- Molecular remodeling of the central auditory pathway in tinnitus revealed by RNA sequencing.Genes & genomics · 2026Article
- Dorsal posterior cingulate cortex encodes the informational value of feedback in human-computer interaction.Scientific reports · 2020Article
- Choice-Selective Neurons in the Auditory Cortex and in Its Striatal Target Encode Reward Expectation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Effect of sequential comparison on active processing of sound duration.Human brain mapping · 2017Article
- Reversal Learning in Humans and Gerbils: Dynamic Control Network Facilitates Learning.Frontiers in neuroscience · 2016Article
- Feedback associated with expectation for larger-reward improves visuospatial working memory performances in children with ADHD.Developmental cognitive neuroscience · 2015Article
- It's Sad but I Like It: The Neural Dissociation Between Musical Emotions and Liking in Experts and Laypersons.Frontiers in human neuroscience · 2015Article
- Functional neuroimaging of visuospatial working memory tasks enables accurate detection of attention deficit and hyperactivity disorder.NeuroImage. Clinical · 2015Article
- Auditory processing disorders with and without central auditory discrimination deficits.Journal of the Association for Research in Otolaryngology : JARO · 2014Article
- Biological impact of auditory expertise across the life span: musicians as a model of auditory learning.Hearing research · 2014Review
- Ventral tegmental area activation promotes firing precision and strength through circuit inhibition in the primary auditory cortex.Frontiers in neural circuits · 2014Article
- Positive and negative reinforcement activate human auditory cortex.Frontiers in human neuroscience · 2013Article
- Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Animal experiments provide evidence that learning to associate an auditory stimulus with a reward causes representational changes in auditory cortex. However, most studies did not investigate the temporal formation of learning-dependent plasticity during the task but rather compared auditory cortex receptive fields before and after conditioning. We here present a functional magnetic resonance imaging study on learning-related plasticity in the human auditory cortex during operant appetitive conditioning. Participants had to learn to associate a specific category of frequency-modulated tones with a reward. Only participants who learned this association developed learning-dependent plasticity in left auditory cortex over the course of the experiment. No differential responses to reward predicting and nonreward predicting tones were found in auditory cortex in nonlearners. In addition, learners showed similar learning-induced differential responses to reward-predicting and nonreward-predicting tones in the ventral tegmental area and the nucleus accumbens, two core regions of the dopaminergic neurotransmitter system. This may indicate a dopaminergic influence on the formation of learning-dependent plasticity in auditory cortex, as it has been suggested by previous animal studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.