Evidence map›Paper›PMID 22610477›Full record

ArticleJAMA2012

Inhaled hypertonic saline in infants and young children with cystic fibrosis.

Elliott C Dasenbrook, Michael W Konstan

Abstract readEditorialComment
In one paragraph

Article in JAMA, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Palliative drug treatments for breathlessness in cystic fibrosis.The Cochrane database of systematic reviews · 2020
    Pooled it
  2. Palliative drug treatments for breathlessness in cystic fibrosis.The Cochrane database of systematic reviews · 2017
    Pooled it
  3. Review
  4. Preliminary comparison of normalized T1 and non-contrast perfusion MRI assessments of regional lung disease in cystic fibrosis patients.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2017
    Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Elliott C Dasenbrook
Michael W Konstan

Funding

Translational Research in Cystic FibrosisP30DK027651 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI DRUMM, MITCHELL L · 1986 to 2014
$15.6M
NIDDK NIH HHS P30 DK027651
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cystic FibrosisFemaleHumansLungMaleSaline Solution, HypertonicSaline Solution, Hypertonic

Identifiers

PMID22610477
PMCPMC4255264

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.