Evidence map›Paper›PMID 22609885›Full record

Trial reportBone marrow transplantation2013

Pre-transplantation iron chelation in patients with MDS or acute leukemia and iron overload undergoing myeloablative allo-SCT.

P Armand, M-M Sainvil, H T Kim, J Rhodes, C Cutler, V T Ho, J Koreth, E P Alyea, E J Neufeld, R Y Kwong and 2 more

Open access · greenAbstract readClinical TrialLetter
In one paragraph

Trial report in Bone marrow transplantation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Iron overload in allogeneic hematopoietic cell transplantation outcome: a meta-analysis.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2014
    Pooled it
  2. Trial
  3. Review
  4. Review
  5. Iron overload in the HCT patient: a review.Bone marrow transplantation · 2021
    Review
  6. Article
  7. Iron and leukemia: new insights for future treatments.Journal of experimental & clinical cancer research : CR · 2019
    Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

P Armand
M-M Sainvil
H T Kim
J Rhodes
C Cutler
V T Ho
J Koreth
E P Alyea
E J Neufeld
R Y Kwong
R J Soiffer
J H Antin
Harvard University · USBoston Children's Hospital · USBoston University · USBrigham and Women's Hospital · USDana-Farber Cancer Institute · USStony Brook University · US

Funding

Project 3: Humoral Targets and B Cell Biology in Chronic Graft-vs.-Host DiseaseP01CA142106 · NCI · DANA-FARBER CANCER INST · PI CUTLER, COREY S · 2009 to 2019
$17.5M
Prognostic Impact and Arrhythmic Potential of Peri-infarct Zone by Cardiac MRIR01HL091157 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI KWONG, RAYMOND Y · 2008 to 2012
$2.3M
NCI NIH HHS CA142106-06NCI NIH HHS P01 CA142106NHLBI NIH HHS R01 HL091157
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Chelation TherapyHematopoietic Stem Cell TransplantationTransplantation ConditioningAdultDeferoxamineDrug MonitoringEarly Termination of Clinical TrialsFeasibility StudiesFollow-Up StudiesHumansInfusions, IntravenousInfusions, SubcutaneousIron Chelating AgentsIron OverloadLeukemia, Myeloid, AcuteMiddle AgedDeferoxamineIron Chelating AgentsMyeloablative Agonists

Identifiers

PMID22609885
PMCPMC3954511
OpenAlexW2031583561

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.