ArticleGastroenterology2012
Validation of a simple classification system for endoscopic diagnosis of small colorectal polyps using narrow-band imaging.
Article in Gastroenterology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 13 registered trials, which are not on this map. Cited by 220 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Resect and Discard Extension to Fuji Intelligent Color Enhancement (FICE) of Narrow Band Imaging International Colorectal Endoscopic (NicE) Classification
Prospective Study of Real-time Diagnosis of Colorectal Polyps Using Narrow-Band Imaging: Gangnam-ReaDi Study
Computer Assisted Optical Assessment of Small Colorectal Polyps
Prospective Randomised Study Comparing Modified Sano's (MS) Classification and NBI International Colorectal Endoscopic (NICE) for Differentiating Colorectal Lesions
Validation of the NICE Classification Using Pentax Chromoendoscopy (I-scan and Optical Enhancement System
A Prospective Randomized Study of Colonoscopy Using Blue Laser Imaging and White Light Imaging in the Detection and Differentiation of Colonic Polyps
Interpretation of Endoscopic Characteristics of Colorectal Polyps With Blue Light Imaging
Computer Assisted Detection & Selection of Serrated Adenomas and Neoplastic Polyps - a New Clinical DRAft
National Colorectal Polyp Care for Diagnosis, Classification and Resection
A Randomised Controlled Trial of the Prediction of Diminutive/Small Polyp Histology: a Comparison Between Didactic Training Versus Self-directed Computer Based Training
Evaluation of ArTificial Intelligence System (Gi-Genius) for adenoMa dEtection in Lynch Syndrome. A Randomized, Parallel, Multicenter, Controlled Trial. TIMELY Study.
EndoscoPic Submucosal dIssection Using geL Versus glycerOl for Submucosal iNjection: a Randomized Controlled Multicentric Trial (EPSILON)
Real-World Validation of an Artificial Intelligence Characterization Support (CADx) System for Prediction of Polyp Histology in Colonoscopy: A Prospective Multicentre Study
Who cites it
220 citing papers in PubMed, 4 syntheses or guidelines pooled it, 577 citations in OpenAlex.
- Diagnostic performance of magnifying endoscopy with narrow-band imaging in differentiating neoplastic colorectal polyps from non-neoplastic colorectal polyps: a meta-analysis.Journal of gastroenterology · 2018Pooled it
- Colonic lesion characterization in inflammatory bowel disease: A systematic review and meta-analysis.World journal of gastroenterology · 2018Pooled it
- Early rectal cancer: the European Association for Endoscopic Surgery (EAES) clinical consensus conference.Surgical endoscopy · 2015Guideline
- Pooled it
- Comparison of methylene blue dye-based chromoendoscopy and Fujifilm virtual chromoendoscopy (blue light imaging and linked color imaging) for dysplasia detection in inflammatory bowel disease: a prospective single-center randomized study.BMC gastroenterology · 2026Trial
- Trial
- Cold snare polypectomy versus cold endoscopic mucosal resection for small colorectal polyps: a multicenter randomized controlled trial.Surgical endoscopy · 2023Trial
- Interactive training versus self-driven training in the prediction of colorectal polyp histology by trainees using the NICE classification.BMC gastroenterology · 2023Trial
- Effect of educational lecture on the diagnostic accuracy of Japan NBI Expert Team classification for colorectal lesions.BMC gastroenterology · 2021Trial
- Comparison of enhanced laparoscopic imaging techniques in endometriosis surgery: a diagnostic accuracy study.Surgical endoscopy · 2020Trial
- Detection and recurrence rate of transurethral resection of bladder tumors by narrow-band imaging: Prospective, randomized comparison with white light cystoscopy.Investigative and clinical urology · 2018Trial
- Trial
- The role of narrow band imaging in colorectal polyp detection.Bosnian journal of basic medical sciences · 2017Trial
- Trial
- Two-stage optical system for colorectal polyp assessments.Surgical endoscopy · 2016Trial
- Usefulness of narrow-band imaging with dual-focus magnification for differential diagnosis of small colorectal polyps.Surgical endoscopy · 2015Trial
- Diagnostic performance and limitations of magnifying narrow-band imaging in screening endoscopy of early gastric cancer: a prospective multicenter feasibility study.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2014Trial
- AMFF-Net: An Adaptive Multi-Layer Feature Fusion Network Based on ConvNeXtV2-B for Medical Image Classification.Bioengineering (Basel, Switzerland) · 2026Article
- Efficacy of image-enhanced endoscopy for colorectal polyp detection.Clinical endoscopy · 2026Review
- Assessment of Red Dichromatic Imaging with Indigo Carmine for Identifying Deep Submucosal Invasion in Colorectal Tumors: A Pilot Study.Diagnostics (Basel, Switzerland) · 2026Article
160 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND &
aimsAlmost all colorectal polyps ≤ 5 mm are benign, yet current practice requires costly pathologic analysis. We aimed to develop and evaluate the validity of a simple narrow-band imaging (NBI)-based classification system for differentiating hyperplastic from adenomatous polyps.
methodsThe study was conducted in 4 phases: (1) evaluation of accuracy and reliability of histologic prediction by NBI-experienced colonoscopists; (2) development of a classification based on color, vessels, and surface pattern criteria, using a modified Delphi method; (3) validation of the component criteria by people not experienced in endoscopy or NBI analysis (25 medical students, 19 gastroenterology fellows) using 118 high-definition colorectal polyp images of known histology; and (4) validation of the classification system by NBI-trained gastroenterology fellows, using still images. We performed a pilot evaluation during real-time colonoscopy.
resultsWe developed a classification system for the endoscopic diagnosis of colorectal polyp histology and established its predictive validity. When all 3 criteria were used, the specificity ranged from 94.9% to 100% and the combined sensitivity ranged from 8.5% to 61.0%. The specificities of the individual criteria were lower although the sensitivities were higher. During real-time colonoscopy, endoscopists made diagnoses with high confidence for 75% of consecutive small colorectal polyps, with 89% accuracy, 98% sensitivity, and 95% negative predictive values.
conclusionsWe developed and established the validity of an NBI classification system that can be used to diagnose colorectal polyps. In preliminary real-time evaluation, the system allowed endoscopic diagnoses of colorectal polyp histology.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.