Evidence map›Paper›PMID 22608776›Full record

ArticleJournal of chromatography. A2012

Qualitative analysis of algal secretions with multiple mass spectrometric platforms.

Tobias Kind, John K Meissen, Dawei Yang, Fernando Nocito, Arpana Vaniya, Yu-Shen Cheng, Jean S Vandergheynst, Oliver Fiehn

Open access · greenAbstract read
In one paragraph

Article in Journal of chromatography. A, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 80 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Bioassay-guided isolation of glycolipids from the seaweedResearch in pharmaceutical sciences · 2020
    Article
  9. Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2019
    Article
  10. Article
  11. Article
  12. ImpairedJournal of the American Society of Nephrology : JASN · 2018
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Stress response of Chlorella pyrenoidosa to nitro-aromatic compounds.Environmental science and pollution research international · 2015
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Tobias KindUC Davis Genome Center-Metabolomics, University of California, Davis, CA 95616, USA. tkind@ucdavis.edu
John K Meissen
Dawei Yang
Fernando Nocito
Arpana Vaniya
Yu-Shen Cheng
Jean S Vandergheynst
Oliver Fiehn
University of California, Davis · US

Funding

Metabolomics Network for Drug Response PhenotypeRC2GM092729 · NIGMS · DUKE UNIVERSITY · PI KADDURAH-DAOUK, RIMA F · 2009 to 2010
$4.5M
Environmental Impact on Perinatal Lung MetabolismR01ES013932 · NIEHS · UNIVERSITY OF CALIFORNIA DAVIS · PI FIEHN, OLIVER · 2005 to 2009
$2.2M
Identification of Muscle-Specific Biomarkers of Fatty Acid beta-OxidationR01DK078328 · NIDDK · U.S. AGRICULTURAL RESEARCH SERVICE · PI ADAMS, SEAN HARRISON · 2008 to 2012
$1.8M
NIDDK NIH HHS R01 DK078328NIEHS NIH HHS ES013932NIEHS NIH HHS R01 ES013932NIGMS NIH HHS RC2 GM092729
6 · The paper itself

Abstract

Lipid secretions from algae pose a great opportunity for engineering biofueler feedstocks. The lipid exudates could be interesting from a process engineering perspective because lipids could be collected directly from the medium without harvesting and disrupting cells. We here report on the extracellular secretions of algal metabolites from the strain UTEX 2341 (Chlorella minutissima) into the culture medium. No detailed analysis of these lipid secretions has been performed to date. Using multiple mass spectrometric platforms, we observed around 1000 compounds and were able to annotate 50 lipids by means of liquid chromatography coupled to accurate mass quadrupole time-of-flight mass spectrometry (LC-QTOF), direct infusion with positive and negative electrospray ion trap mass spectrometry and gas chromatography coupled to mass spectrometry (GC-MS). These compounds were annotated by tandem mass spectral (MS/MS) database matching and retention time range filtering. We observed a series of triacylglycerols (TG), sulfoquinovosyldiacylglycerols (SQDG), phosphatidylinositols and phosphatidylglycerols, as well as betaine lipids diacylglyceryl-N,N,N-trimethylhomoserines (DGTS).

Indexed as

BiofuelsChlorellaChromatography, LiquidGas Chromatography-Mass SpectrometryHydrophobic and Hydrophilic InteractionsLipid MetabolismLipidsTandem Mass SpectrometryBiofuelsLipids

Identifiers

PMID22608776
PMCPMC3746802
OpenAlexW2064535416

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.