ArticleAmerican journal of preventive medicine2012
A population approach to precision medicine.
Article in American journal of preventive medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
70 citing papers in PubMed, 2 syntheses or guidelines pooled it, 159 citations in OpenAlex.
- Cancer risk assessment tools in primary care: a systematic review of randomized controlled trials.Annals of family medicine · 2015Pooled it
- Personalized respiratory medicine: exploring the horizon, addressing the issues. Summary of a BRN-AJRCCM workshop held in Barcelona on June 12, 2014.American journal of respiratory and critical care medicine · 2015Pooled it
- Assessment of a Precision Medicine Analysis of a Behavioral Counseling Strategy to Improve Adherence to Diabetes Self-management Among Youth: A Post Hoc Analysis of the FLEX Trial.JAMA network open · 2019Trial
- Hookups, hashtags, and health: A Latent Class Analysis of social media, mental health and sleep among MSM in Paris, France.SSM. Mental health · 2026Article
- Collection of implementation-related data in pragmatic clinical trials: a cross-sectional study from the NIH Pragmatic Trials Collaboratory.Implementation science communications · 2026Article
- Genetic ancestry proportion influences risk of adverse events from tuberculosis treatment in Brazil.Human genetics · 2026Observational
- WMRE2030: integrating wearable devices, multi-omics, and artificial intelligence-driven real-time feedback into a daily-scale closed-loop framework for a new era of precision exercise.Frontiers in physiology · 2026Review
- The Role of Virtual Reality in Personalized Medicine: Advancing Prediction, Prevention, and Participation.Journal of medical systems · 2025Review
- Transforming Health in Developing Nations: Paving the Way for an Integrated Health System.Journal of healthcare leadership · 2025Article
- Adaptation of a digital health intervention for rural adults: application of the Framework for Reporting Adaptations and Modifications-Enhanced.Frontiers in digital health · 2025Article
- Sex differences in delivery and neonatal characteristics of new-borns from the "MAMI-MED" cohort.Frontiers in public health · 2025Article
- Genetic ancestry in population pharmacogenomics unravels distinct geographical patterns related to drug toxicity.iScience · 2024Article
- Applying Implementation Science to Advance Electronic Health Record-Driven Learning Health Systems: Case Studies, Challenges, and Recommendations.Journal of medical Internet research · 2024Article
- Empowering Healthcare through Precision Medicine: Unveiling the Nexus of Social Factors and Trust.Healthcare (Basel, Switzerland) · 2023Article
- Malmö Breast ImaginG database: objectives and development.Journal of medical imaging (Bellingham, Wash.) · 2023Article
- Personalized multicomponent exercise programs using smartphone technology among older people: protocol for a randomized controlled trial.BMC geriatrics · 2021Article
- Personalized, Predictive, Participatory, Precision, and Preventive (P5) Medicine in Rotator Cuff Tears.Journal of personalized medicine · 2021Article
- Polygenic risk scores in the clinic: new perspectives needed on familiar ethical issues.Genome medicine · 2021Article
- The building blocks of precision oral health in early childhood: the ZOE 2.0 study.Journal of public health dentistry · 2020Article
- Leveraging implementation science to improve implementation outcomes in precision medicine.American journal of translational research · 2020Review
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
The term P4 medicine is used to denote an evolving field of medicine that uses systems biology approaches and information technologies to enhance wellness rather than just treat disease. Its four components include predictive, preventive, personalized, and participatory medicine. In the current paper, it is argued that in order to fulfill the promise of P4 medicine, a "fifth P" must be integrated-the population perspective-into each of the other four components. A population perspective integrates predictive medicine into the ecologic model of health; applies principles of population screening to preventive medicine; uses evidence-based practice to personalize medicine; and grounds participatory medicine on the three core functions of public health: assessment, policy development, and assurance. Population sciences-including epidemiology; behavioral, social, and communication sciences; and health economics, implementation science, and outcomes research-are needed to show the value of P4 medicine. Balanced strategies that implement both population- and individual-level interventions can best maximize health benefits, minimize harm, and avoid unnecessary healthcare costs.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.