ArticleEmerging infectious diseases2012
Intrafamilial circulation of Tropheryma whipplei, France.
Article in Emerging infectious diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 63 citations in OpenAlex.
- Neurological Manifestations in Whipple's Disease: A Scoping Review of Clinical Features, Laboratory Findings, and Neuroimaging Characteristics of 111 Cases.European journal of neurology · 2026Article
- Multidisciplinary management of Whipple's disease complicated with rectal stenosis from multidisciplinary nursing management: A case study.Pakistan journal of medical sciences · 2026Article
- Clinically Suspected Whipple Disease Presenting with Acute Kidney Injury as the Initial Manifestation and Complicated by Severe Pneumonia Requiring Veno-Venous Extracorporeal Membrane Oxygenation.Infection and drug resistance · 2026Article
- Whipple Disease Initial Presentation as Supraclavicular Lymphadenopathy in a Patient With Rheumatoid Arthritis: A Diagnostic Challenge.International journal of surgical pathology · 2025Article
- A case of acute community-acquired pneumonia caused byIDCases · 2025Article
- Article
- Whipple Disease Presenting as Isolated Transverse Myelitis with Permanent Neurological Damage in a Patient with Systemic Lupus Erythematosus: A Case Report of a Difficult Diagnosis with a Literature Review.Infectious disease reports · 2024Article
- Tropheryma whipplei Intestinal Colonization in Migrant Children, Greece.Emerging infectious diseases · 2022Article
- Article
- Whipple disease diagnosed by enteroscopy: first case report in Colombia of an underdiagnosed disease and literature review.BMC gastroenterology · 2020Review
- An atypical case of Whipple's disease presenting as fever of unknown origin: A brief review.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2019Article
- Clinical Manifestations, Treatment, and Diagnosis of Tropheryma whipplei Infections.Clinical microbiology reviews · 2017Review
- FluorescenceFrontiers in medicine · 2017Article
- Tropheryma whipplei as a Cause of Epidemic Fever, Senegal, 2010-2012.Emerging infectious diseases · 2016Article
- Arthralgia and blood culture-negative endocarditis in middle Age Men suggest tropheryma whipplei infection: report of two cases and review of the literature.BMC infectious diseases · 2015Article
- High prevalence of Tropheryma whipplei in Lao kindergarten children.PLoS neglected tropical diseases · 2015Article
- Complicated Whipple's disease and endocarditis following tumor necrosis factor inhibitors.World journal of cardiology · 2014Article
- Tropheryma whipplei genotypes 1 and 3, Central Europe.Emerging infectious diseases · 2013Article
- Looking for Tropheryma whipplei source and reservoir in rural Senegal.The American journal of tropical medicine and hygiene · 2013Article
- Whipple's Disease: Our Own Experience and Review of the Literature.Gastroenterology research and practice · 2013Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tropheryma whipplei, which causes Whipple disease, has been detected in 4% of fecal samples from the general adult population of France. To identify T. whipplei within families, we conducted serologic and molecular studies, including genotyping, on saliva, feces, and serum from 74 relatives of 13 patients with classic Whipple disease, 5 with localized chronic T. whipplei infection, and 3 carriers. Seroprevalence was determined by Western blot and compared with 300 persons from the general population. We detected T. whipplei in 24 (38%) of 64 fecal samples and 7 (10%) of 70 saliva samples from relatives but found no difference between persons related by genetics and marriage. The same circulating genotype occurred significantly more often in families than in other persons. Seroprevalence was higher among relatives (23 [77%] of 30) than in the general population (143 [48%] of 300). The high prevalence of T. whipplei within families suggests intrafamilial circulation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.