ReviewTrends in endocrinology and metabolism: TEM2012
Nocturnin: at the crossroads of clocks and metabolism.
Review in Trends in endocrinology and metabolism: TEM, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 70 citations in OpenAlex.
- Article
- Article
- Gene Characterization of Nocturnin Paralogues in Goldfish: Full Coding Sequences, Structure, Phylogeny and Tissue Expression.International journal of molecular sciences · 2023Article
- Brain transcriptome of gobies inhabiting natural COEvolutionary applications · 2023Article
- NR1D1 downregulation in astrocytes induces a phenotype that is detrimental to cocultured motor neurons.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022Article
- Chronoradiobiology of Breast Cancer: The Time Is Now to Link Circadian Rhythm and Radiation Biology.International journal of molecular sciences · 2022Review
- Emerging Insight Into the Role of Circadian Clock Gene BMAL1 in Cellular Senescence.Frontiers in endocrinology · 2022Review
- Dim Light at Night Disturbs Molecular Pathways of Lipid Metabolism.International journal of molecular sciences · 2020Article
- Human carnosinase 1 overexpression aggravates diabetes and renal impairment in BTBRJournal of molecular medicine (Berlin, Germany) · 2020Article
- Hypolipidemic effect of Alisma orientale (Sam.) Juzep on gut microecology and liver transcriptome in diabetic rats.PloS one · 2020Article
- Working against the biological clock: a review for the Occupational Physician.Industrial health · 2019Review
- The metabolites NADPNature communications · 2019Article
- Plasmodium male gametocyte development and transmission are critically regulated by the two putative deadenylases of the CAF1/CCR4/NOT complex.PLoS pathogens · 2019Article
- Article
- Circadian Clock Genes in the Metabolism of Non-alcoholic Fatty Liver Disease.Frontiers in physiology · 2019Review
- Maintenance of Kidney Metabolic Homeostasis by PPAR Gamma.International journal of molecular sciences · 2018Review
- Nicotinamide Adenine Dinucleotide Metabolism and Neurodegeneration.Antioxidants & redox signaling · 2018Review
- Circadian Posttranscriptional Regulatory Mechanisms in Mammals.Cold Spring Harbor perspectives in biology · 2018Review
- Cardinal Epigenetic Role of non-coding Regulatory RNAs in Circadian Rhythm.Molecular neurobiology · 2018Review
- Potential Roles of Dec and Bmal1 Genes in Interconnecting Circadian Clock and Energy Metabolism.International journal of molecular sciences · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Many aspects of metabolism exhibit daily rhythmicity under the control of endogenous circadian clocks, and disruptions in circadian timing result in dysfunctions associated with the metabolic syndrome. Nocturnin (Noc) is a robustly rhythmic gene that encodes a deadenylase thought to be involved in the removal of polyA tails from mRNAs. Mice lacking the Noc gene display resistance to diet-induced obesity and hepatic steatosis, due in part to reduced lipid trafficking in the small intestine. In addition, Noc appears to play important roles in other tissues and has been implicated in lipid metabolism, adipogenesis, glucose homeostasis, inflammation and osteogenesis. Therefore, Noc is a potential key post-transcriptional mediator in the circadian control of many metabolic processes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.