Evidence map›Paper›PMID 22607376›Full record

ReviewJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2012

Minimizing risk of nephrogenic systemic fibrosis in cardiovascular magnetic resonance.

Theresa Reiter, Oliver Ritter, Martin R Prince, Peter Nordbeck, Christoph Wanner, Eike Nagel, Wolfgang Rudolf Bauer

Abstract readReview
In one paragraph

Review in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. High-throughput gadobutrol-enhanced CMR: a time and dose optimization study.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2017
    Trial
  2. Trial
  3. Trial
  4. Contrast Agents for Enhanced Bioimaging: A Comprehensive Review.Chembiochem : a European journal of chemical biology · 2026
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Radiomics and deep learning for myocardial scar screening in hypertrophic cardiomyopathy.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2022
    Article
  11. Review
  12. Diagnostic imaging of cardiac amyloidosis.Nature reviews. Cardiology · 2020
    Review
  13. Article
  14. Article
  15. Article
  16. Detection of cardiac amyloidosis withEuropean journal of nuclear medicine and molecular imaging · 2019
    Article
  17. ADPKD-what the radiologist should know.The British journal of radiology · 2019
    Review
  18. Review
  19. Review
  20. Updates on the Role of Imaging in Cardiac Sarcoidosis.Current treatment options in cardiovascular medicine · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Theresa ReiterDepartment of Internal Medicine I, Division of Cardiology, University Hospital Wuerzburg, Wuerzburg, Germany. Reiter_T@medizin.uni-wuerzburg.de
Oliver Ritter
Martin R Prince
Peter Nordbeck
Christoph Wanner
Eike Nagel
Wolfgang Rudolf Bauer

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nephrogenic Systemic Fibrosis is a rare condition appearing only in patients with severe renal impairment or failure and presents with dermal lesions and involvement of internal organs. Although many cases are mild, an estimated 5% have a progressive debilitating course. To date, there is no known effective treatment thus stressing the necessity of ample prevention measures. An association with the use of Gadolinium based contrast agents (GBCA) makes Nephrogenic Systemic Fibrosis a potential side effect of contrast enhanced magnetic resonance imaging and offers the opportunity for prevention by limiting use of gadolinium based contrast agents in renal failure patients. In itself toxic, Gadolinium is embedded into chelates that allow its safe use as a contrast agent. One NSF theory is that Gadolinium chelates distribute into the extracellular fluid compartment and set Gadolinium ions free, depending on multiple factors among which the duration of chelates exposure is directly related to the renal function. Major medical societies both in Europe and in North America have developed guidelines for the usage of GBCA. Since the establishment of these guidelines and the increased general awareness of this condition, the occurrence of NSF has been nearly eliminated. Giving an overview over the current knowledge of NSF pathobiochemistry, pathogenesis and treatment options this review focuses on the guidelines of the European Medicines Agency, the European Society of Urogenital Radiology, the FDA and the American College of Radiology from 2008 up to 2011 and the transfer of this knowledge into every day practice.

Indexed as

Nephrogenic Fibrosing DermopathyCardiovascular DiseasesContrast MediaGadoliniumGlobal HealthHumansIncidenceMagnetic Resonance Imaging, CineRisk FactorsContrast MediaGadolinium

Identifiers

PMID22607376
PMCPMC3409035

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.