ArticleNutrition & metabolism2012
Serum 25-hydroxyvitamin D3 and body composition in an elderly cohort from Germany: a cross-sectional study.
Article in Nutrition & metabolism, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Guideline
- Three doses of vitamin D, bone mineral density, and geometry in older women during modest weight control in a 1-year randomized controlled trial.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017Trial
- The effect of vitamin D supplementation on serum 25(OH)D in thin and obese women.The Journal of steroid biochemistry and molecular biology · 2013Trial
- Association of vitamin D levels with anthropometric and adiposity indicators across all age groups: a systematic review of epidemiologic studies.Endocrine connections · 2024Article
- Vitamin D status among Kashmiri tribal population: A cross-sectional community-based study.The Indian journal of medical research · 2022Article
- How can the orthopedic surgeon ensure optimal vitamin D status in patients operated for an osteoporotic fracture?Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021Review
- Vitamin D status of overweight and obese Bangladeshi adults.Journal of family medicine and primary care · 2020Article
- Targeted 25-hydroxyvitamin D concentration measurements and vitamin DEuropean journal of clinical nutrition · 2020Review
- Linking the metabolic syndrome and obesity with vitamin D status: risks and opportunities for improving cardiometabolic health and well-being.Diabetes, metabolic syndrome and obesity : targets and therapy · 2019Article
- Association of serum vitamin D with change in weight and total body fat in a German cohort of older adults.European journal of clinical nutrition · 2016Article
- Vitamin D deficiency and airflow limitation in the Baltimore Longitudinal Study of Ageing.European journal of clinical investigation · 2015Article
- Associations of serum 25-hydroxycholecalciferol and parathyroid hormone with serum lipids differ by sex and vitamin D status.Public health nutrition · 2015Article
- Association of vitamin D with adiposity measures and other determinants in a cross-sectional study of Cypriot adolescents.Public health nutrition · 2015Article
- Sex-specific determinants of serum 25-hydroxyvitamin D3 concentrations in an elderly German cohort: a cross-sectional study.Nutrition & metabolism · 2015Article
- Dietary intake and main food sources of vitamin D as a function of age, sex, vitamin D status, body composition, and income in an elderly German cohort.Food & nutrition research · 2014Article
- Variation in the MC4R gene is associated with bone phenotypes in elderly Swedish women.PloS one · 2014Article
- The beneficial role of vitamin D in obesity: possible genetic and cell signaling mechanisms.Nutrition journal · 2013Review
- The association between serum vitamin d levels with general and abdominal obesity among patients with migraine.International journal of preventive medicine · 2013Article
- Vitamin d levels in subjects with prostate cancer compared to age-matched controls.Prostate cancer · 2012Article
- Role of Parathyroid Hormone in Determination of Fat Mass in Patients with Vitamin D Deficiency.Indian journal of endocrinology and metabolismArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEmerging evidence indicates that there is an association between vitamin D and obesity. The aim of this study was to investigate whether the level of serum 25-hydroxyvitamin D3 [25(OH)D3] in the elderly is influenced by parameters of anthropometry and body composition independent of potential confounding lifestyle factors and the level of serum intact parathyroid hormone (iPTH).
methodsCross-sectional data of 131 independently living participants (90 women, 41 men; aged 66-96 years) of the longitudinal study on nutrition and health status in senior citizens of Giessen, Germany were analysed. Concentrations of 25(OH)D3 and iPTH were ascertained by an electrochemiluminescence immunoassay. Body composition was measured by a bioelectrical impedance analysis. We performed univariate and multiple regression analyses to examine the influence of body composition on 25(OH)D3 with adjustments for age, iPTH and lifestyle factors.
resultsIn univariate regression analyses, 25(OH)D3 was associated with body mass index (BMI), hip circumference and total body fat (TBF) in women, but not in men. Using multiple regression analyses, TBF was shown to be a negative predictor of 25(OH)D3 levels in women even after controlling for age, lifestyle and iPTH (ß = -0.247; P = 0.016), whereas the associations between BMI, hip circumference and 25(OH)D3 lost statistical significance after adjusting for iPTH. In men, 25(OH)D3 was not affected by anthropometric or body composition variables.
conclusionsThe results indicate that 25(OH)D3 levels are affected by TBF, especially in elderly women, independent of lifestyle factors and iPTH.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.