Evidence map›Paper›PMID 22606037›Full record

ReviewInternational journal of molecular sciences2012

Filamentous bacteriophage fd as an antigen delivery system in vaccination.

Antonella Prisco, Piergiuseppe De Berardinis

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 59 citations in OpenAlex.

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  16. Review
  17. HER2-Positive Breast Cancer Immunotherapy: A Focus on Vaccine Development.Archivum immunologiae et therapiae experimentalis · 2020
    Review
  18. Phage display as a tool for vaccine and immunotherapy development.Bioengineering & translational medicine · 2020
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Antonella PriscoInstitute of Genetics and Biophysics, CNR, via P. Castellino 111, 80131, Naples, Italy.
Piergiuseppe De BerardinisInstitute of Protein Biochemistry, CNR, via P. Castellino 111, 80131, Naples, Italy.
Institute of Genetics and Biophysics · ITInstitute of Protein Biochemistry · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peptides displayed on the surface of filamentous bacteriophage fd are able to induce humoral as well as cell-mediated immune responses, which makes phage particles an attractive antigen delivery system to design new vaccines. The immune response induced by phage-displayed peptides can be enhanced by targeting phage particles to the professional antigen presenting cells, utilizing a single-chain antibody fragment that binds dendritic cell receptor DEC-205. Here, we review recent advances in the use of filamentous phage fd as a platform for peptide vaccines, with a special focus on the use of phage fd as an antigen delivery platform for peptide vaccines in Alzheimer's Disease and cancer.

Indexed as

Amyloid beta-PeptidesAnimalsBacteriophage M13CapsidCapsid ProteinsCell Surface Display TechniquesDendritic CellsDrug CarriersMicePeptide LibraryT-Lymphocytes, CytotoxicVaccinationVaccines, SubunitAmyloid beta-PeptidesCapsid Proteinscoat protein, Bacteriophage M13Drug CarriersPeptide LibraryVaccines, Subunitantigen delivery systembacteriophage fdvaccine

Identifiers

PMID22606037
PMCPMC3344273
OpenAlexW2033683294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.