Evidence map›Paper›PMID 22604767›Full record

ArticleBMJ case reports2012

Acute hepatitis E virus infection and autoimmune thyroiditis: yet another trigger?

Franz Ludwig Dumoulin, Hanna Liese

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
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  11. Article
  12. A Case of Graves' Disease Accompanied with Acute Hepatitis A Virus Infection.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2018
    Article
  13. Hepatitis E virus and neurological injury.Nature reviews. Neurology · 2016
    Review
  14. Review
  15. Review
  16. Hepatitis E: an underestimated emerging threat.Therapeutic advances in infectious disease
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Franz Ludwig DumoulinDepartment of Medicine, Gemeinschaftskrankenhaus Bonn, Bonn, Germany. f.dumoulin@gk-bonn.de
Hanna Liese
Gemeinschaftskrankenhaus Havelhöhe · DEGerman Doctors · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A middle aged woman, previously healthy with the exception of mild seasonal asthma was presented with signs of acute hepatitis. The further investigation showed acute hepatitis E virus infection associated with autoimmune thyroiditis. Treatment was started with propranolol and carbimazol whereupon hepatitis and hyperthyroidism resolved. The authors think that the observed association of acute hepatitis E virus infection and autoimmune thyroiditis suggests a role of hepatitis E virus as putative trigger of autoimmune thyroiditis. The alternative possibility of thyroid dysfunction due to pre-existing autoantibodies cannot be completely excluded but seems to be unlikely given the very mild course of seasonal asthma in this patient.

Indexed as

Adrenergic beta-AntagonistsAntithyroid AgentsCarbimazoleDiagnosis, DifferentialDrug Therapy, CombinationFemaleHepatitis EHumansLiver Function TestsMiddle AgedPropranololThyroiditis, AutoimmuneAdrenergic beta-AntagonistsAntithyroid AgentsCarbimazolePropranolol

Identifiers

PMID22604767
PMCPMC3339187
OpenAlexW2071540837

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.