Evidence map›Paper›PMID 22596320›Full record

ReviewNature reviews. Genetics2012

The fate and future of patents on human genes and genetic diagnostic methods.

Isabelle Huys, Gert Matthijs, Geertrui Van Overwalle

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Genetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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  4. Eteplirsen in the treatment of Duchenne muscular dystrophy.Drug design, development and therapy · 2017
    Review
  5. Article
  6. Review
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Isabelle HuysFaculty of Pharmaceutical Sciences and Centre for Intellectual Property Rights, University of Leuven, Herestraat 49, B-3000 Leuven, Belgium.
Gert Matthijs
Geertrui Van Overwalle

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the 1970s, patents on human genes and genetic diagnostic methods have been granted under the assumption that they stimulate the development of diagnostic methods and therapeutic products. However, the principles and practices of patenting vary between jurisdictions. Do patent holders, researchers, clinicians and patients really benefit from this heterogeneous patent system? We discuss the problems that result from the current system and suggest how they might be solved by altering the way in which patents are granted and/or licensed.

Indexed as

ForecastingGenetic Predisposition to DiseaseGenetics, MedicalGenetic TestingHumansLicensureMolecular Diagnostic TechniquesPatents as Topic

Identifiers

PMID22596320

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.