Evidence map›Paper›PMID 22596257›Full record

GuidelineBlood2012

A perspective on the selection of unrelated donors and cord blood units for transplantation.

Stephen R Spellman, Mary Eapen, Brent R Logan, Carlheinz Mueller, Pablo Rubinstein, Michelle I Setterholm, Ann E Woolfrey, Mary M Horowitz, Dennis L Confer, Carolyn K Hurley and 2 more

Abstract readPractice Guideline
In one paragraph

Guideline in Blood, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Guideline
  4. Trial
  5. Trial
  6. Article
  7. Classical HLA Allele and Haplotype Frequency Estimates in US Populations.bioRxiv : the preprint server for biology · 2026
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Observational
  15. Article
  16. HLA Matching in Unrelated Stem Cell Transplantation up to Date.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2019
    Review
  17. Human Leukocyte Antigen and Red Blood Cells Impact Umbilical Cord Blood CD34International journal of molecular sciences · 2019
    Article
  18. Review
  19. [How we do anti-HLA antibodies detection of quality control better].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Stephen R SpellmanCenter for International Blood and Marrow Transplant Research, Division of Hematology and Oncology, Department of Medicine, Medical College of Wisconsin, 9200 West Wisconsin Ave., Milwaukee, WI 53226, USA.
Mary Eapen
Brent R Logan
Carlheinz Mueller
Pablo Rubinstein
Michelle I Setterholm
Ann E Woolfrey
Mary M Horowitz
Dennis L Confer
Carolyn K Hurley
National Marrow Donor Program
Center for International Blood and Marrow Transplant Research

Funding

Data Resource for Analyzing Blood &Marrow TransplantsU24CA076518 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI Amy M Moskop, Bronwen Shaw · 1998 to 2026
$105.2M
NCI NIH HHS U24 CA076518NCI NIH HHS U24-CA76518
6 · The paper itself

Abstract

Selection of a suitable graft for allogeneic hematopoietic stem cell transplantation involves consideration of both donor and recipient characteristics. Of primary importance is sufficient donor-recipient HLA matching to ensure engraftment and acceptable rates of GVHD. In this Perspective, the National Marrow Donor Program and the Center for International Blood and Marrow Transplant Research provide guidelines, based on large studies correlating graft characteristics with clinical transplantation outcomes, on appropriate typing strategies and matching criteria for unrelated adult donor and cord blood graft selection.

Indexed as

AdultAdult Stem CellsCord Blood Stem Cell TransplantationDonor SelectionHematopoietic Stem Cell TransplantationHistocompatibility TestingHumansInfant, NewbornPeripheral Blood Stem Cell TransplantationTissue DonorsTransplantation ImmunologyUnited States

Identifiers

PMID22596257
PMCPMC3398760

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.