ArticleJournal of perinatology : official journal of the California Perinatal Association2012
Risk of stillbirth at extremes of birth weight between 20 to 41 weeks gestation.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 48 citations in OpenAlex.
- Impact of SGA, AGA, and LGA birthweight subclassification on NICU mortality risk identification: a cohort study.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Does infant birthweight percentile identify mothers at risk of severe morbidity? A Canadian population-based cohort study.Maternal health, neonatology and perinatology · 2025Article
- Placental Pathology Findings in Unexplained Pregnancy Losses.Reproductive sciences (Thousand Oaks, Calif.) · 2024Article
- Are U-shaped relationships between risk factors and outcomes artifactual?Journal of diabetes · 2022Article
- Reduced fetal growth velocity precedes antepartum fetal death.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2021Article
- Alterations to Placental Glucocorticoid Receptor Expression with Alcohol Consumption.Reproductive sciences (Thousand Oaks, Calif.) · 2021Article
- Stillbirth maternity care measurement and associated factors in population-based surveys: EN-INDEPTH study.Population health metrics · 2021Article
- Characteristics of Stillbirths Associated With Diabetes in a Diverse U.S. Cohort.Obstetrics and gynecology · 2020Article
- Impact of free maternal health care policy on maternal health care utilization and perinatal mortality in Ghana: protocol design for historical cohort study.Reproductive health · 2020Article
- Rate, determinants, and causes of stillbirth in Jordan: Findings from the Jordan Stillbirth and Neonatal Deaths Surveillance (JSANDS) system.BMC pregnancy and childbirth · 2020Article
- Large-for-gestational age and stillbirth: is there a role for antenatal testing?Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2019Article
- Placental Abnormalities Associated With Childbirth.Academic forensic pathology · 2019Review
- The Role of Infection and Inflammation in Stillbirths: Parallels with SIDS?Frontiers in immunology · 2015Review
- Cytokine Levels in Late Pregnancy: Are Female Infants Better Protected Against Inflammation?Frontiers in immunology · 2015Article
- Fetal growth and risk of stillbirth: a population-based case-control study.PLoS medicine · 2014Article
- Studying and preventing stillbirth: what are the methodological issues?Journal of perinatology : official journal of the California Perinatal Association · 2012Article
Corrections and comments
- Commented on by
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine the risk of stillbirth between 20 to 41 weeks gestation, at highly detailed weight percentiles, including extreme degrees of small (SGA) and large (LGA) for gestational age birth weight. STUDY
designWe completed a population-based study of all births in Ontario, Canada between 2002 and 2007. We included 767, 016 liveborn and 4,697 stillborn singletons delivered between 20 and 41 weeks gestation. Smoothed birthweight percentile curves were generated for males and females, combining livebirths and stillbirths. Quantile regression was used to calculate sex-specific absolute birthweight differences and 95% confidence intervals (CI) between stillborns vs liveborns at various gestational ages. Logistic regression was used to calculate the odds ratios (OR) for stillbirth at various sex-specific birthweight percentiles, including <1st and ≥ 99th percentile. OR were adjusted for maternal age and parity.
resultAt the 10th percentile, stillborns weighed significantly less than liveborns starting at 24 weeks gestation. By 32 weeks, this difference was 590 g (95% CI 430 to 750) for males and 551 g (95% CI 345 to 448) for females. A reverse J-shaped association was observed between birthweight percentile and risk of stillbirth across all gestational ages. Relative to the 40th to 60th percentile referent, the adjusted OR for stillbirth was 9.63 (95% CI 8.39 to 11.06) at a birth weight <1st percentile. At ≥ 99th percentile, the adjusted OR was 2.24 (95% CI 1.76 to 2.86). The risk of stillbirth at extreme birthweight percentiles was robustly observed across gestational ages.
conclusionSubstantial birthweight differences exist between stillborns and newborns. As a possible hallmark of impending intrauterine death, severe SGA and LGA may each be potential targets for future stillbirth prevention initiatives.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.