ArticleGenetics in medicine : official journal of the American College of Medical Genetics2012
Association between health-service use and multiplex genetic testing.
Article in Genetics in medicine : official journal of the American College of Medical Genetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Internet-Based Direct-to-Consumer Genetic Testing: A Systematic Review.Journal of medical Internet research · 2015Pooled it
- Genetic and environmental risk assessment and colorectal cancer screening in an average-risk population: a randomized trial.Annals of internal medicine · 2014Trial
- Equity in Genomic Medicine.Annual review of genomics and human genetics · 2022Review
- Considerations for developing regulations for direct-to-consumer genetic testing: a scoping review using the 3-I framework.Journal of community genetics · 2022Article
- Genomics-informed weight management in primary care: anticipated public interest.Personalized medicine · 2018Article
- Behavioural changes, sharing behaviour and psychological responses after receiving direct-to-consumer genetic test results: a systematic review and meta-analysis.Journal of community genetics · 2018Review
- Does personal genome testing drive service utilization in an adult preventive medicine clinic?Journal of community genetics · 2017Article
- Prescription medication changes following direct-to-consumer personal genomic testing: findings from the Impact of Personal Genomics (PGen) Study.Genetics in medicine : official journal of the American College of Medical Genetics · 2017Article
- Personal Genomic Testing for Cancer Risk: Results From the Impact of Personal Genomics Study.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2017Article
- Social determinants of family health history collection.Journal of community genetics · 2016Article
- Direct-to-consumer genomics on the scales of autonomy.Journal of medical ethics · 2015Article
- Exploring barriers to payer utilization of genetic counselors.Journal of genetic counseling · 2015Article
- Discussing race-related limitations of genomic testing for colon cancer risk: implications for education and counseling.Social science & medicine (1982) · 2014Article
- Horizon scanning for translational genomic research beyond bench to bedside.Genetics in medicine : official journal of the American College of Medical Genetics · 2014Article
- The role of weight, race, and health care experiences in care use among young men and women.Obesity (Silver Spring, Md.) · 2014Article
- Design, methods, and participant characteristics of the Impact of Personal Genomics (PGen) Study, a prospective cohort study of direct-to-consumer personal genomic testing customers.Genome medicine · 2014Article
- Predictive genetic testing, risk communication, and risk perception: an international expert meeting in Berlin, Germany.Journal of community genetics · 2014Article
- Attitudes towards Social Networking and Sharing Behaviors among Consumers of Direct-to-Consumer Personal Genomics.Journal of personalized medicine · 2013Article
- Direct-to-Consumer Genetic Testing and Personal Genomics Services: A Review of Recent Empirical Studies.Current genetic medicine reports · 2013Article
- Molecular genetic testing and the future of clinical genomics.Nature reviews. Genetics · 2013Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
purposeThe objective of this work was to examine whether offers of multiplex genetic testing increase health-care utilization among healthy patients aged 25-40 years. The identification of genetic variants associated with common disease is accelerating rapidly. "Multiplex tests" that give individuals feedback on large panels of genetic variants have proliferated. Availability of these test results may prompt consumers to use more health-care services.
methodsA total of 1,599 continuously insured adults aged 25-40 years were surveyed and offered a multiplex genetic susceptibility test for eight common health conditions. Health-care utilization from automated records was compared in 12-month pre- and posttest periods among persons who completed a baseline survey only (68.7%), those who visited a study website but opted not to test (17.8%), and those who chose the multiplex genetic susceptibility test (13.6%).
resultsIn the pretest period, persons choosing genetic testing used an average of 1.02 physician visits per quarter as compared with 0.93 and 0.82 for the baseline-only and Web-only groups, respectively (P < 0.05). There were no statistically significant differences by group in the pretest use of any common medical tests or procedures associated with four common health conditions. When changes in physician and medical test/procedure use in the posttest period were compared among the groups, no statistically significant differences were observed for any utilization category.
conclusionsPersons offered and completing multiplex genetic susceptibility testing used more physician visits before testing, but testing was not associated with subsequent changes in use. This study supports the supposition that multiplex genetic testing offers can be provided directly to the patients in such a way that use of health services is not inappropriately increased.
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