ArticleThe European journal of neuroscience2012
Striatal dopamine modulates song spectral but not temporal features through D1 receptors.
Article in The European journal of neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 78 citations in OpenAlex.
- Punishment-induced behavioral and neurophysiological variability reveals dopamine-dependent selection of kinematic movement parameters.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Trial
- Neural mechanism of dopamine modulating singing related behavior in songbirds: an updated review.PeerJ · 2025Review
- Social context affects sequence modification learning in birdsong.Frontiers in psychology · 2025Article
- Neurochemical Characterization of Dopaminoceptive Cells in Song Control Nuclei of Canaries and Their Activation During Song Production: A Multiplex Fluorescent In Situ Hybridization Study.The Journal of comparative neurology · 2024Article
- Divergent projections from locus coeruleus to the corticobasal ganglia system and ventral tegmental area of the adult male zebra finch.The Journal of comparative neurology · 2023Article
- Learning in the time of COVID: insights from the zebra finch - a social vocal-learner.Current opinion in neurobiology · 2021Review
- Unilateral vocal nerve resection alters neurogenesis in the avian song system in a region-specific manner.PloS one · 2021Article
- Manipulations of inhibition in cortical circuitry differentially affect spectral and temporal features of Bengalese finch song.Journal of neurophysiology · 2020Article
- Blocking Opioid Receptors in a Songbird Cortical Region Modulates the Acoustic Features and Levels of Female-Directed Singing.Frontiers in neuroscience · 2020Article
- Altering Opioid Neuromodulation in the Songbird Basal Ganglia Modulates Vocalizations.Frontiers in neuroscience · 2019Article
- Article
- Song-associated reward correlates with endocannabinoid-related gene expression in male European starlings (Sturnus vulgaris).Neuroscience · 2017Article
- Prodynorphin and kappa opioid receptor mRNA expression in the brain relates to social status and behavior in male European starlings.Behavioural brain research · 2017Article
- Review
- Dopaminergic Contributions to Vocal Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Song in an Affiliative Context Relates to the Neural Expression of Dopamine- and Neurotensin-Related Genes in Male European Starlings.Brain, behavior and evolution · 2016Article
- Reduced vocal variability in a zebra finch model of dopamine depletion: implications for Parkinson disease.Physiological reports · 2015Article
- Neurotensin neural mRNA expression correlates with vocal communication and other highly-motivated social behaviors in male European starlings.Physiology & behavior · 2015Article
- Predicting plasticity: acute context-dependent changes to vocal performance predict long-term age-dependent changes.Journal of neurophysiology · 2015Article
- Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
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Abstract
The activity of midbrain dopaminergic neurons and their projection to the basal ganglia (BG) are thought to play a critical role in the acquisition of motor skills through reinforcement learning, as well as in the expression of learned motor behaviors. The precise role of BG dopamine (DA) in mediating and modulating motor performance and learning, however, remains unclear. In songbirds, a specialized portion of the BG is responsible for song learning and plasticity. Previously we found that DA acts on D1 receptors in Area X to modulate the BG output signal and thereby trigger changes in song variability. Here, we investigate the effect of D1 receptor blockade in the BG on song behavior in the zebra finch. We report that this manipulation abolishes social context-dependent changes in variability not only in harmonic stacks, but also in other types of syllables. However, song timing seems not to be modulated by this BG DA signal. Indeed, injections of a D1 antagonist in the BG altered neither song duration nor the change of song duration with social context. Finally, D1 receptor activation in the BG was not necessary for the modulation of other features of song, such as the number of introductory notes or motif repetitions. Together, our results suggest that activation of D1 receptors in the BG is necessary for the modulation of fine acoustic features of song with social context, while it is not involved in the regulation of song timing and structure at a larger time scale.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.