ArticleScandinavian journal of gastroenterology2012
Functional bowel symptoms, fibromyalgia and fatigue: a food-induced triad?
Article in Scandinavian journal of gastroenterology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 49 citations in OpenAlex.
- The self-management work of food hypersensitivity.PloS one · 2021Article
- Altered levels of cytokines in patients with irritable bowel syndrome are not correlated with fatigue.International journal of general medicine · 2018Article
- Systemic symptoms in irritable bowel syndrome: An investigative study on the role of enterocyte disintegrity, endotoxemia and inflammation.Molecular medicine reports · 2016Article
- Self-Reported Food Hypersensitivity: Prevalence, Characteristics, and Comorbidities in the Norwegian Women and Cancer Study.PloS one · 2016Article
- The spectrum of noncoeliac gluten sensitivity.Nature reviews. Gastroenterology & hepatology · 2015Review
- Food allergy in irritable bowel syndrome: The case of non-celiac wheat sensitivity.World journal of gastroenterology · 2015Review
- Celiac symptoms in patients with fibromyalgia: a cross-sectional study.Rheumatology international · 2015Article
- An insight into the gastrointestinal component of fibromyalgia: clinical manifestations and potential underlying mechanisms.Rheumatology international · 2015Review
- Indole - the scent of a healthy 'inner soil'.Microbial ecology in health and disease · 2015Article
- Tryptophan: 'essential' for the pathogenesis of irritable bowel syndrome?Scandinavian journal of gastroenterology · 2014Article
- Intestinal staphylococcal small colony variants: a cause of medically unexplained physical symptoms?Microbial ecology in health and disease · 2014Article
- Clinical impact of a gluten-free diet on health-related quality of life in seven fibromyalgia syndrome patients with associated celiac disease.BMC gastroenterology · 2013Article
- Fructose and lactose intolerance and malabsorption testing: the relationship with symptoms in functional gastrointestinal disorders.Alimentary pharmacology & therapeutics · 2013Article
- Remarkable prevalence of coeliac disease in patients with irritable bowel syndrome plus fibromyalgia in comparison with those with isolated irritable bowel syndrome: a case-finding study.Arthritis research & therapy · 2013Article
- Overlap between functional GI disorders and other functional syndromes: what are the underlying mechanisms?Neurogastroenterology and motility · 2012Review
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivePatients with perceived food hypersensitivity typically present with multiple health complaints. We aimed to assess the severity of their intestinal and extra-intestinal symptoms. MATERIALS AND
methodsIn a prospective study, 84 patients referred to our outpatient clinic for investigation of perceived food hypersensitivity were enrolled consecutively. Irritable bowel syndrome (IBS) was diagnosed according to the Rome III criteria. Severity and impact of bowel symptoms, fatigue and musculoskeletal pain were evaluated by using the following questionnaires: The IBS Severity Scoring System (IBS-SSS), the Fatigue Impact Scale (FIS), the FibroFatigue Scale (FFS), and visual analogue scales (VAS) for scoring of musculoskeletal pain.
resultsAll but one patient were diagnosed with IBS, 58% with severe symptoms. Extra-intestinal symptoms suggestive of chronic fatigue and fibromyalgia were demonstrated in 85% and 71%, respectively. Neither IgE-mediated food allergy nor organic pathology could explain the patients' symptoms. Nevertheless, malabsorption of fat was demonstrated in 10 of 38 subjects.
conclusionsPerceived food hypersensitivity may be associated with severe, debilitating illness. The comorbid triad of IBS, chronic fatigue, and musculoskeletal pain is striking and may point to a common underlying cause.
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