ArticleFrontiers in immunology2012
The human intestinal IgA response; burning questions.
Article in Frontiers in immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- A scientific journey through viral immunology, vaccines, and neuroinflammation.Human vaccines & immunotherapeutics · 2026Article
- Gut immune responses and evolution of the gut microbiome-a hypothesis.Discovery immunology · 2023Review
- Building better barriers: how nutrition and undernutrition impact pediatric intestinal health.Frontiers in immunology · 2023Review
- Human gut-associated lymphoid tissues (GALT); diversity, structure, and function.Mucosal immunology · 2021Review
- Vaccine therapy for dysbiosis-related diseases.World journal of gastroenterology · 2020Review
- Article
- IgA and the intestinal microbiota: the importance of being specific.Mucosal immunology · 2020Review
- Local eosinophils are associated with increased IgA subclass levels in the sinonasal mucosa of chronic rhinosinusitis with polyp patients.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2020Article
- Microbiota-Immune Interaction in the Pathogenesis of Gut-Derived Infection.Frontiers in immunology · 2019Review
- Levels of total IgA and IgA subclasses in the serum of chronic rhinosinusitis patients.Medical journal of the Islamic Republic of Iran · 2018Article
- Long-lived plasma cells are generated in mucosal immune responses and contribute to the bone marrow plasma cell pool in mice.Mucosal immunology · 2016Article
- Diversification of memory B cells drives the continuous adaptation of secretory antibodies to gut microbiota.Nature immunology · 2015Article
- Old questions, new tools: does next-generation sequencing hold the key to unraveling intestinal B-cell responses?Mucosal immunology · 2015Review
- Cryptopatches are essential for the development of human GALT.Cell reports · 2013Article
- Liver-spleen axis: intersection between immunity, infections and metabolism.World journal of gastroenterology · 2013Review
- Secretory immunity with special reference to the oral cavity.Journal of oral microbiology · 2013Article
- Secretory IgA: Designed for Anti-Microbial Defense.Frontiers in immunology · 2013Article
- New concepts in the generation and functions of IgA.Nature reviews. Immunology · 2012Review
- The intestinal B-cell response in celiac disease.Frontiers in immunology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The title of this special topic invites us to identify areas in the field of IgA biology that are uncertain or in need of clarification. The inductive phase of the human intestinal IgA response has been a controversial area for some years. Therefore, to structure this review, we have identified key questions that are debated in this field. We have provided explanations of the origins of the uncertainties and have provided our own reasoned answers to the questions we pose.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.