ArticleJournal of clinical microbiology2012
Molecular epidemiologic analysis and antimicrobial resistance of Helicobacter cinaedi isolated from seven hospitals in Japan.
Article in Journal of clinical microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Infected aortic aneurysm caused by Helicobacter cinaedi: case series and systematic review of the literature.BMC infectious diseases · 2020Pooled it
- Pre- and peri-hematopoietic cell transplant management of disseminated non-Helicobacter pylori Helicobacter infection in X-linked agammaglobulinemia: Case series and literature review.Clinical immunology (Orlando, Fla.) · 2026Review
- Bacteremia caused byASM case reports · 2025Article
- Prevalence and diversity of Helicobacter species in captive wild carnivores, and their implications for conservation management of endangered species.BMC veterinary research · 2025Article
- Peritonsillar abscess associated withIDCases · 2024Article
- Recurrent Cellulitis Revealing Helicobacter cinaedi in Patient on Ibrutinib Therapy, France.Emerging infectious diseases · 2023Article
- Determining Infected Aortic Aneurysm Treatment Using Focused Detection of Helicobacter cinaedi.Emerging infectious diseases · 2022Article
- Article
- Helicobacter cinaedi bacteraemia secondary to enterocolitis in an immunocompetent patient.Gut pathogens · 2021Article
- Multi-step genomic dissection of a suspected intra-hospital Helicobacter cinaedi outbreak.Microbial genomics · 2018Article
- Draft Genome Sequence of Helicobacter cinaedi, Compiled by Direct Whole-Genome Sequencing of a Blood Culture-Positive Isolate in Hong Kong.Microbiology resource announcements · 2018Article
- Mutations in Genes Encoding Penicillin-Binding Proteins and Efflux Pumps Play a Role in β-Lactam Resistance in Helicobacter cinaedi.Antimicrobial agents and chemotherapy · 2018Article
- Getting to the Heart of the Matter: A 20-Year-Old Man With Fever, Rash, and Chest Pain.Open forum infectious diseases · 2018Article
- Infected Thoracic Aortic Aneurysm Caused byAnnals of vascular diseases · 2017Article
- Article
- Successful treatment of recurrentJMM case reports · 2016Article
- First case of bacteremia caused by Helicobacter cinaedi in a patient with liver cirrhosis: a case report and literature review.Clinical journal of gastroenterology · 2015Review
- Helicobacter cinaedi infection in patients with diabetes: a case report.SpringerPlus · 2015Article
- Helicobacter cinaedi infection of abdominal aortic aneurysm, Japan.Emerging infectious diseases · 2014Article
- Helicobacter cinaedi and Helicobacter fennelliae transmission in a hospital from 2008 to 2012.Journal of clinical microbiology · 2013Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
Helicobacter cinaedi colonizes the colons of human and animals and can cause colitis, cellulitis, and sepsis in humans, with infections in immunocompromised patients being increasingly recognized. However, methods for analyzing the molecular epidemiology of H. cinaedi are not yet established. A genotyping method involving multilocus sequence typing (MLST) was developed and used to analyze 50 H. cinaedi isolates from Japanese hospitals in addition to 6 reference strains. Pulsed-field gel electrophoresis (PFGE) results were also compared with the MLST results. Based on the genomic information from strain CCUG18818, 21 housekeeping genes were selected as candidates for MLST and were observed to have high homology (96.5 to 100%) between isolates. Following a comparison of the 21 housekeeping genes from 8 H. cinaedi isolates, 7 genes were chosen for MLST, revealing 14 sequence types (STs). The isolates from 3 hospitals belonged to the same STs, but the isolates from the other 4 hospitals belonged to different STs. Isolates belonging to ST6 were analyzed by PFGE and showed similar, but not identical, patterns between isolates. Isolates belonging to ST9, ST10, and ST11, which belonged to the same clonal complex, had the same pattern. All isolates were found to contain mutations in GyrA and the 23S rRNA gene that confer ciprofloxacin and clarithromycin resistance, respectively, in H. cinaedi. These results raise concerns about the increase in H. cinaedi isolates resistant to clarithromycin and ciprofloxacin in Japan.
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Registered trials
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